# Exploring and Distilling Posterior and Prior Knowledge for Radiology Report Generation

arXiv: https://arxiv.org/abs/2106.06963 · HTML: https://mlsanity.com/paper/2106.06963/

## Key facts

- Cited by 162 papers in the map (data through 14 Oct 2026).
- Builds on 32 of its 48 references that are in the map.
- First posted on arXiv 13 Jun 2021.

## Builds on (most cited first, 30 of 32)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Semi-Supervised Classification with Graph Convolutional Networks](https://mlsanity.com/paper/1609.02907/) (2016)
- [Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks](https://mlsanity.com/paper/1908.10084/) (2019)
- [Layer Normalization](https://mlsanity.com/paper/1607.06450/) (2016)
- [CIDEr: Consensus-based Image Description Evaluation](https://mlsanity.com/paper/1411.5726/) (2014)
- [Microsoft COCO Captions: Data Collection and Evaluation Server](https://mlsanity.com/paper/1504.00325/) (2015)
- [Show, Attend and Tell: Neural Image Caption Generation with Visual Attention](https://mlsanity.com/paper/1502.03044/) (2015)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [Show and Tell: A Neural Image Caption Generator](https://mlsanity.com/paper/1411.4555/) (2014)
- [MIMIC-CXR-JPG, a large publicly available database of labeled chest radiographs](https://mlsanity.com/paper/1901.07042/) (2019)
- [Self-critical Sequence Training for Image Captioning](https://mlsanity.com/paper/1612.00563/) (2016)
- [Generating Radiology Reports via Memory-driven Transformer](https://mlsanity.com/paper/2010.16056/) (2020)
- [Knowing When to Look: Adaptive Attention via A Visual Sentinel for Image Captioning](https://mlsanity.com/paper/1612.01887/) (2016)
- [On the Automatic Generation of Medical Imaging Reports](https://mlsanity.com/paper/1711.08195/) (2017)
- [When Radiology Report Generation Meets Knowledge Graph](https://mlsanity.com/paper/2002.08277/) (2020)
- [Hybrid Retrieval-Generation Reinforced Agent for Medical Image Report Generation](https://mlsanity.com/paper/1805.08298/) (2018)
- [TieNet: Text-Image Embedding Network for Common Thorax Disease Classification and Reporting in Chest X-rays](https://mlsanity.com/paper/1801.04334/) (2018)
- [A Hierarchical Approach for Generating Descriptive Image Paragraphs](https://mlsanity.com/paper/1611.06607/) (2016)
- [Knowledge-driven Encode, Retrieve, Paraphrase for Medical Image Report Generation](https://mlsanity.com/paper/1903.10122/) (2019)
- [Automatic Radiology Report Generation based on Multi-view Image Fusion and Medical Concept Enrichment](https://mlsanity.com/paper/1907.09085/) (2019)
- [Learning to Read Chest X-Rays: Recurrent Neural Cascade Model for Automated Image Annotation](https://mlsanity.com/paper/1603.08486/) (2016)
- [Show, Describe and Conclude: On Exploiting the Structure Information of Chest X-Ray Reports](https://mlsanity.com/paper/2004.12274/) (2020)
- [Video Paragraph Captioning Using Hierarchical Recurrent Neural Networks](https://mlsanity.com/paper/1510.07712/) (2015)
- [Aligning Visual Regions and Textual Concepts for Semantic-Grounded Image Representations](https://mlsanity.com/paper/1905.06139/) (2019)
- [Auxiliary Signal-Guided Knowledge Encoder-Decoder for Medical Report Generation](https://mlsanity.com/paper/2006.03744/) (2020)
- [Recurrent Topic-Transition GAN for Visual Paragraph Generation](https://mlsanity.com/paper/1703.07022/) (2017)
- [simNet: Stepwise Image-Topic Merging Network for Generating Detailed and Comprehensive Image Captions](https://mlsanity.com/paper/1808.08732/) (2018)

## Built on by (most cited first, 30 of 162)

- [Transformers in Medical Imaging: A Survey](https://mlsanity.com/paper/2201.09873/) (2022)
- [BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks](https://mlsanity.com/paper/2305.17100/) (2023)
- [MedKLIP: Medical Knowledge Enhanced Language-Image Pre-Training in Radiology](https://mlsanity.com/paper/2301.02228/) (2023)
- [Interactive and Explainable Region-guided Radiology Report Generation](https://mlsanity.com/paper/2304.08295/) (2023)
- [From Show to Tell: A Survey on Deep Learning-based Image Captioning](https://mlsanity.com/paper/2107.06912/) (2021)
- [A Survey of Large Language Models in Medicine: Progress, Application, and Challenge](https://mlsanity.com/paper/2311.05112/) (2023)
- [Dynamic Graph Enhanced Contrastive Learning for Chest X-ray Report Generation](https://mlsanity.com/paper/2303.10323/) (2023)
- [R2GenGPT: Radiology Report Generation with Frozen LLMs](https://mlsanity.com/paper/2309.09812/) (2023)
- [METransformer: Radiology Report Generation by Transformer with Multiple Learnable Expert Tokens](https://mlsanity.com/paper/2304.02211/) (2023)
- [Improving Chest X-Ray Report Generation by Leveraging Warm Starting](https://mlsanity.com/paper/2201.09405/) (2022)
- [PromptMRG: Diagnosis-Driven Prompts for Medical Report Generation](https://mlsanity.com/paper/2308.12604/) (2023)
- [Improving the Factual Correctness of Radiology Report Generation with Semantic Rewards](https://mlsanity.com/paper/2210.12186/) (2022)
- [Competence-based Multimodal Curriculum Learning for Medical Report Generation](https://mlsanity.com/paper/2206.14579/) (2022)
- [Radiology Report Generation with a Learned Knowledge Base and Multi-modal Alignment](https://mlsanity.com/paper/2112.15011/) (2021)
- [Knowledge Matters: Radiology Report Generation with General and Specific Knowledge](https://mlsanity.com/paper/2112.15009/) (2021)
- [AlignTransformer: Hierarchical Alignment of Visual Regions and Disease Tags for Medical Report Generation](https://mlsanity.com/paper/2203.10095/) (2022)
- [KiUT: Knowledge-injected U-Transformer for Radiology Report Generation](https://mlsanity.com/paper/2306.11345/) (2023)
- [Cross-modal Prototype Driven Network for Radiology Report Generation](https://mlsanity.com/paper/2207.04818/) (2022)
- [State Space Model for New-Generation Network Alternative to Transformers: A Survey](https://mlsanity.com/paper/2404.09516/) (2024)
- [A Medical Semantic-Assisted Transformer for Radiographic Report Generation](https://mlsanity.com/paper/2208.10358/) (2022)
- [Automated Radiology Report Generation: A Review of Recent Advances](https://mlsanity.com/paper/2405.10842/) (2024)
- [ORGAN: Observation-Guided Radiology Report Generation via Tree Reasoning](https://mlsanity.com/paper/2306.06466/) (2023)
- [A Systematic Evaluation of GPT-4V's Multimodal Capability for Medical Image Analysis](https://mlsanity.com/paper/2310.20381/) (2023)
- [Utilizing Longitudinal Chest X-Rays and Reports to Pre-Fill Radiology Reports](https://mlsanity.com/paper/2306.08749/) (2023)
- [CXPMRG-Bench: Pre-training and Benchmarking for X-ray Medical Report Generation on CheXpert Plus Dataset](https://mlsanity.com/paper/2410.00379/) (2024)
- [HERGen: Elevating Radiology Report Generation with Longitudinal Data](https://mlsanity.com/paper/2407.15158/) (2024)
- [Explainable Deep Learning Methods in Medical Image Classification: A Survey](https://mlsanity.com/paper/2205.04766/) (2022)
- [Cascaded Latent Diffusion Models for High-Resolution Chest X-ray Synthesis](https://mlsanity.com/paper/2303.11224/) (2023)
- [SceneTrilogy: On Human Scene-Sketch and its Complementarity with Photo and Text](https://mlsanity.com/paper/2204.11964/) (2022)
- [Style-Aware Radiology Report Generation with RadGraph and Few-Shot Prompting](https://mlsanity.com/paper/2310.17811/) (2023)

## Abstract (arXiv)

Automatically generating radiology reports can improve current clinical practice in diagnostic radiology. On one hand, it can relieve radiologists from the heavy burden of report writing; On the other hand, it can remind radiologists of abnormalities and avoid the misdiagnosis and missed diagnosis. Yet, this task remains a challenging job for data-driven neural networks, due to the serious visual and textual data biases. To this end, we propose a Posterior-and-Prior Knowledge Exploring-and-Distilling approach (PPKED) to imitate the working patterns of radiologists, who will first examine the abnormal regions and assign the disease topic tags to the abnormal regions, and then rely on the years of prior medical knowledge and prior working experience accumulations to write reports. Thus, the PPKED includes three modules: Posterior Knowledge Explorer (PoKE), Prior Knowledge Explorer (PrKE) and Multi-domain Knowledge Distiller (MKD). In detail, PoKE explores the posterior knowledge, which provides explicit abnormal visual regions to alleviate visual data bias; PrKE explores the prior knowledge from the prior medical knowledge graph (medical knowledge) and prior radiology reports (working experience) to alleviate textual data bias. The explored knowledge is distilled by the MKD to generate the final reports. Evaluated on MIMIC-CXR and IU-Xray datasets, our method is able to outperform previous state-of-the-art models on these two datasets.