# An Interaction-based Convolutional Neural Network (ICNN) Towards Better Understanding of COVID-19 X-ray Images

arXiv: https://arxiv.org/abs/2106.06911 · HTML: https://mlsanity.com/paper/2106.06911/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 16 of its 57 references that are in the map.
- First posted on arXiv 13 Jun 2021.

## Builds on (most cited first, 16 of 16)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [Learning Deep Features for Discriminative Localization](https://mlsanity.com/paper/1512.04150/) (2015)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [Rich feature hierarchies for accurate object detection and semantic segmentation](https://mlsanity.com/paper/1311.2524/) (2013)
- [Towards A Rigorous Science of Interpretable Machine Learning](https://mlsanity.com/paper/1702.08608/) (2017)
- [Explanation in Artificial Intelligence: Insights from the Social Sciences](https://mlsanity.com/paper/1706.07269/) (2017)
- [The Mythos of Model Interpretability](https://mlsanity.com/paper/1606.03490/) (2016)
- [A Survey of the Recent Architectures of Deep Convolutional Neural Networks](https://mlsanity.com/paper/1901.06032/) (2019)
- [Deep Image Retrieval: Learning global representations for image search](https://mlsanity.com/paper/1604.01325/) (2016)
- [Benchmarking Attribution Methods with Relative Feature Importance](https://mlsanity.com/paper/1907.09701/) (2019)
- [Deep-COVID: Predicting COVID-19 From Chest X-Ray Images Using Deep Transfer Learning](https://mlsanity.com/paper/2004.09363/) (2020)
- [Multi-scale Orderless Pooling of Deep Convolutional Activation Features](https://mlsanity.com/paper/1403.1840/) (2014)
- [Chester: A Web Delivered Locally Computed Chest X-Ray Disease Prediction System](https://mlsanity.com/paper/1901.11210/) (2019)

## Abstract (arXiv)

The field of Explainable Artificial Intelligence (XAI) aims to build explainable and interpretable machine learning (or deep learning) methods without sacrificing prediction performance. Convolutional Neural Networks (CNNs) have been successful in making predictions, especially in image classification. However, these famous deep learning models use tens of millions of parameters based on a large number of pre-trained filters which have been repurposed from previous data sets. We propose a novel Interaction-based Convolutional Neural Network (ICNN) that does not make assumptions about the relevance of local information. Instead, we use a model-free Influence Score (I-score) to directly extract the influential information from images to form important variable modules. We demonstrate that the proposed method produces state-of-the-art prediction performance of 99.8% on a real-world data set classifying COVID-19 Chest X-ray images without sacrificing the explanatory power of the model. This proposed design can efficiently screen COVID-19 patients before human diagnosis, and will be the benchmark for addressing future XAI problems in large-scale data sets.