# TED-net: Convolution-free T2T Vision Transformer-based Encoder-decoder Dilation network for Low-dose CT Denoising

arXiv: https://arxiv.org/abs/2106.04650 · HTML: https://mlsanity.com/paper/2106.04650/

## Key facts

- Cited by 21 papers in the map (data through 14 Oct 2026).
- Builds on 20 of its 35 references that are in the map.
- First posted on arXiv 8 Jun 2021.

## Builds on (most cited first, 20 of 20)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Training data-efficient image transformers & distillation through attention](https://mlsanity.com/paper/2012.12877/) (2020)
- [Rethinking Attention with Performers](https://mlsanity.com/paper/2009.14794/) (2020)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [Tokens-to-Token ViT: Training Vision Transformers from Scratch on ImageNet](https://mlsanity.com/paper/2101.11986/) (2021)
- [CvT: Introducing Convolutions to Vision Transformers](https://mlsanity.com/paper/2103.15808/) (2021)
- [Pre-Trained Image Processing Transformer](https://mlsanity.com/paper/2012.00364/) (2020)
- [DialoGPT: Large-Scale Generative Pre-training for Conversational Response Generation](https://mlsanity.com/paper/1911.00536/) (2019)
- [Transformer in Transformer](https://mlsanity.com/paper/2103.00112/) (2021)
- [Learning Texture Transformer Network for Image Super-Resolution](https://mlsanity.com/paper/2006.04139/) (2020)
- [DeeBERT: Dynamic Early Exiting for Accelerating BERT Inference](https://mlsanity.com/paper/2004.12993/) (2020)
- [Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN)](https://mlsanity.com/paper/1702.00288/) (2017)
- [HOTR: End-to-End Human-Object Interaction Detection with Transformers](https://mlsanity.com/paper/2104.13682/) (2021)
- [Low Dose CT Image Denoising Using a Generative Adversarial Network with Wasserstein Distance and Perceptual Loss](https://mlsanity.com/paper/1708.00961/) (2017)
- [Can Deep Learning Outperform Modern Commercial CT Image Reconstruction Methods?](https://mlsanity.com/paper/1811.03691/) (2018)
- [Quadratic Autoencoder (Q-AE) for Low-dose CT Denoising](https://mlsanity.com/paper/1901.05593/) (2019)
- [TransCT: Dual-path Transformer for Low Dose Computed Tomography](https://mlsanity.com/paper/2103.00634/) (2021)

## Built on by (most cited first, 21 of 21)

- [Transformers in Medical Imaging: A Survey](https://mlsanity.com/paper/2201.09873/) (2022)
- [Advances in Medical Image Analysis with Vision Transformers: A Comprehensive Review](https://mlsanity.com/paper/2301.03505/) (2023)
- [CTformer: Convolution-free Token2Token Dilated Vision Transformer for Low-dose CT Denoising](https://mlsanity.com/paper/2202.13517/) (2022)
- [Transformers in Medical Image Analysis: A Review](https://mlsanity.com/paper/2202.12165/) (2022)
- [Class-Aware Adversarial Transformers for Medical Image Segmentation](https://mlsanity.com/paper/2201.10737/) (2022)
- [Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectives](https://mlsanity.com/paper/2206.01136/) (2022)
- [HUMUS-Net: Hybrid unrolled multi-scale network architecture for accelerated MRI reconstruction](https://mlsanity.com/paper/2203.08213/) (2022)
- [Vision Transformers in Medical Computer Vision -- A Contemplative Retrospection](https://mlsanity.com/paper/2203.15269/) (2022)
- [Transformers in Healthcare: A Survey](https://mlsanity.com/paper/2307.00067/) (2023)
- [A Comprehensive Survey of Transformers for Computer Vision](https://mlsanity.com/paper/2211.06004/) (2022)
- [LIT-Former: Linking In-plane and Through-plane Transformers for Simultaneous CT Image Denoising and Deblurring](https://mlsanity.com/paper/2302.10630/) (2023)
- [DenoMamba: A fused state-space model for low-dose CT denoising](https://mlsanity.com/paper/2409.13094/) (2024)
- [Recent Progress in Transformer-based Medical Image Analysis](https://mlsanity.com/paper/2208.06643/) (2022)
- [Vision Transformers in Medical Imaging: A Review](https://mlsanity.com/paper/2211.10043/) (2022)
- [Transformers-based architectures for stroke segmentation: A review](https://mlsanity.com/paper/2403.18637/) (2024)
- [Simulation of Arbitrary Level Contrast Dose in MRI Using an Iterative Global Transformer Model](https://mlsanity.com/paper/2307.11980/) (2023)
- [Manifoldron: Direct Space Partition via Manifold Discovery](https://mlsanity.com/paper/2201.05279/) (2022)
- [3D Shuffle-Mixer: An Efficient Context-Aware Vision Learner of Transformer-MLP Paradigm for Dense Prediction in Medical Volume](https://mlsanity.com/paper/2204.06779/) (2022)
- [TransMorph: Transformer for unsupervised medical image registration](https://mlsanity.com/paper/2111.10480/) (2021)
- [Cross-domain Denoising for Low-dose Multi-frame Spiral Computed Tomography](https://mlsanity.com/paper/2304.10839/) (2023)
- [A-IDE : Agent-Integrated Denoising Experts](https://mlsanity.com/paper/2503.16780/) (2025)

## Abstract (arXiv)

Low dose computed tomography is a mainstream for clinical applications. How-ever, compared to normal dose CT, in the low dose CT (LDCT) images, there are stronger noise and more artifacts which are obstacles for practical applications. In the last few years, convolution-based end-to-end deep learning methods have been widely used for LDCT image denoising. Recently, transformer has shown superior performance over convolution with more feature interactions. Yet its ap-plications in LDCT denoising have not been fully cultivated. Here, we propose a convolution-free T2T vision transformer-based Encoder-decoder Dilation net-work (TED-net) to enrich the family of LDCT denoising algorithms. The model is free of convolution blocks and consists of a symmetric encoder-decoder block with sole transformer. Our model is evaluated on the AAPM-Mayo clinic LDCT Grand Challenge dataset, and results show outperformance over the state-of-the-art denoising methods.
