# GCN-MIF: Graph Convolutional Network with Multi-Information Fusion for Low-dose CT Denoising

arXiv: https://arxiv.org/abs/2105.07146 · HTML: https://mlsanity.com/paper/2105.07146/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 14 of its 41 references that are in the map.
- First posted on arXiv 15 May 2021.

## Builds on (most cited first, 14 of 14)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Improved Training of Wasserstein GANs](https://mlsanity.com/paper/1704.00028/) (2017)
- [Self-Attention with Relative Position Representations](https://mlsanity.com/paper/1803.02155/) (2018)
- [Dynamic Edge-Conditioned Filters in Convolutional Neural Networks on Graphs](https://mlsanity.com/paper/1704.02901/) (2017)
- [Generative Adversarial Network in Medical Imaging: A Review](https://mlsanity.com/paper/1809.07294/) (2018)
- [Low-Dose CT with a Residual Encoder-Decoder Convolutional Neural Network (RED-CNN)](https://mlsanity.com/paper/1702.00288/) (2017)
- [Low Dose CT Image Denoising Using a Generative Adversarial Network with Wasserstein Distance and Perceptual Loss](https://mlsanity.com/paper/1708.00961/) (2017)
- [Can Deep Learning Outperform Modern Commercial CT Image Reconstruction Methods?](https://mlsanity.com/paper/1811.03691/) (2018)
- [3D Convolutional Encoder-Decoder Network for Low-Dose CT via Transfer Learning from a 2D Trained Network](https://mlsanity.com/paper/1802.05656/) (2018)
- [Quadratic Autoencoder (Q-AE) for Low-dose CT Denoising](https://mlsanity.com/paper/1901.05593/) (2019)
- [Deep Graph-Convolutional Image Denoising](https://mlsanity.com/paper/1907.08448/) (2019)
- [Cycle Consistent Adversarial Denoising Network for Multiphase Coronary CT Angiography](https://mlsanity.com/paper/1806.09748/) (2018)
- [Cycle-free CycleGAN using Invertible Generator for Unsupervised Low-Dose CT Denoising](https://mlsanity.com/paper/2104.08538/) (2021)

## Abstract (arXiv)

Being low-level radiation exposure and less harmful to health, low-dose computed tomography (LDCT) has been widely adopted in the early screening of lung cancer and COVID-19. LDCT images inevitably suffer from the degradation problem caused by complex noises. It was reported that deep learning (DL)-based LDCT denoising methods using convolutional neural network (CNN) achieved impressive denoising performance. Although most existing DL-based methods (e.g., encoder-decoder framework) can implicitly utilize non-local and contextual information via downsampling operator and 3D CNN, the explicit multi-information (i.e., local, non-local, and contextual) integration may not be explored enough. To address this issue, we propose a novel graph convolutional network-based LDCT denoising model, namely GCN-MIF, to explicitly perform multi-information fusion for denoising purpose. Concretely, by constructing intra- and inter-slice graph, the graph convolutional network is introduced to leverage the non-local and contextual relationships among pixels. The traditional CNN is adopted for the extraction of local information. Finally, the proposed GCN-MIF model fuses all the extracted local, non-local, and contextual information. Extensive experiments show the effectiveness of our proposed GCN-MIF model by quantitative and visualized results. Furthermore, a double-blind reader study on a public clinical dataset is also performed to validate the usability of denoising results in terms of the structural fidelity, the noise suppression, and the overall score. Models and code are available at https://github.com/tonyckc/GCN-MIF_demo.