# Automated Primary Hyperparathyroidism Screening with Neural Networks

arXiv: https://arxiv.org/abs/2105.02386 · HTML: https://mlsanity.com/paper/2105.02386/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 4 of its 11 references that are in the map.
- First posted on arXiv 6 May 2021.

## Builds on (most cited first, 4 of 4)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [A Patient-Centric Dataset of Images and Metadata for Identifying Melanomas Using Clinical Context](https://mlsanity.com/paper/2008.07360/) (2020)
- [Evaluating Progress on Machine Learning for Longitudinal Electronic Healthcare Data](https://mlsanity.com/paper/2010.01149/) (2020)

## Abstract (arXiv)

Primary Hyperparathyroidism(PHPT) is a relatively common disease, affecting about one in every 1,000 adults. However, screening for PHPT can be difficult, meaning it often goes undiagnosed for long periods of time. While looking at specific blood test results independently can help indicate whether a patient has PHPT, often these blood result levels can all be within their respective normal ranges despite the patient having PHPT. Based on the clinic data from the real world, in this work, we propose a novel approach to screening PHPT with neural network (NN) architecture, achieving over 97% accuracy with common blood values as inputs. Further, we propose a second model achieving over 99% accuracy with additional lab test values as inputs. Moreover, compared to traditional PHPT screening methods, our NN models can reduce the false negatives of traditional screening methods by 99%.