# R2U3D: Recurrent Residual 3D U-Net for Lung Segmentation

arXiv: https://arxiv.org/abs/2105.02290 · HTML: https://mlsanity.com/paper/2105.02290/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 14 of its 31 references that are in the map.
- First posted on arXiv 5 May 2021.

## Builds on (most cited first, 14 of 14)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Squeeze-and-Excitation Networks](https://mlsanity.com/paper/1709.01507/) (2017)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [Recurrent Residual Convolutional Neural Network based on U-Net (R2U-Net) for Medical Image Segmentation](https://mlsanity.com/paper/1802.06955/) (2018)
- [Explainable deep learning models in medical image analysis](https://mlsanity.com/paper/2005.13799/) (2020)
- [The History Began from AlexNet: A Comprehensive Survey on Deep Learning Approaches](https://mlsanity.com/paper/1803.01164/) (2018)
- [Fully Dense UNet for 2D Sparse Photoacoustic Tomography Artifact Removal](https://mlsanity.com/paper/1808.10848/) (2018)
- [3D Segmentation with Exponential Logarithmic Loss for Highly Unbalanced Object Sizes](https://mlsanity.com/paper/1809.00076/) (2018)
- [D-UNet: a dimension-fusion U shape network for chronic stroke lesion segmentation](https://mlsanity.com/paper/1908.05104/) (2019)
- [X-Net: Brain Stroke Lesion Segmentation Based on Depthwise Separable Convolution and Long-range Dependencies](https://mlsanity.com/paper/1907.07000/) (2019)
- [AUNet: Attention-guided dense-upsampling networks for breast mass segmentation in whole mammograms](https://mlsanity.com/paper/1810.10151/) (2018)
- [Under the Hood of Neural Networks: Characterizing Learned Representations by Functional Neuron Populations and Network Ablations](https://mlsanity.com/paper/2004.01254/) (2020)

## Built on by (most cited first, 2 of 2)

- [Medical Artificial Intelligence for Early Detection of Lung Cancer: A Survey](https://mlsanity.com/paper/2410.14769/) (2024)
- [CT-LungNet: A Deep Learning Framework for Precise Lung Tissue Segmentation in 3D Thoracic CT Scans](https://mlsanity.com/paper/2212.13971/) (2022)

## Abstract (arXiv)

3D lung segmentation is essential since it processes the volumetric information of the lungs, removes the unnecessary areas of the scan, and segments the actual area of the lungs in a 3D volume. Recently, the deep learning model, such as U-Net outperforms other network architectures for biomedical image segmentation. In this paper, we propose a novel model, namely, Recurrent Residual 3D U-Net (R2U3D), for the 3D lung segmentation task. In particular, the proposed model integrates 3D convolution into the Recurrent Residual Neural Network based on U-Net. It helps learn spatial dependencies in 3D and increases the propagation of 3D volumetric information. The proposed R2U3D network is trained on the publicly available dataset LUNA16 and it achieves state-of-the-art performance on both LUNA16 (testing set) and VESSEL12 dataset. In addition, we show that training the R2U3D model with a smaller number of CT scans, i.e., 100 scans, without applying data augmentation achieves an outstanding result in terms of Soft Dice Similarity Coefficient (Soft-DSC) of 0.9920.