# Ridge Regression Neural Network for Pediatric Bone Age Assessment

arXiv: https://arxiv.org/abs/2104.07785 · HTML: https://mlsanity.com/paper/2104.07785/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 32 references that are in the map.
- First posted on arXiv 15 Apr 2021.

## Builds on (most cited first, 9 of 9)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [SmoothGrad: removing noise by adding noise](https://mlsanity.com/paper/1706.03825/) (2017)
- [Grad-CAM++: Improved Visual Explanations for Deep Convolutional Networks](https://mlsanity.com/paper/1710.11063/) (2017)
- [Deep Learning in Neural Networks: An Overview](https://mlsanity.com/paper/1404.7828/) (2014)
- [Smooth Grad-CAM++: An Enhanced Inference Level Visualization Technique for Deep Convolutional Neural Network Models](https://mlsanity.com/paper/1908.01224/) (2019)
- [Pediatric Bone Age Assessment Using Deep Convolutional Neural Networks](https://mlsanity.com/paper/1712.05053/) (2017)
- [Residual Attention based Network for Hand Bone Age Assessment](https://mlsanity.com/paper/1901.05876/) (2018)

## Abstract (arXiv)

Bone age is an important measure for assessing the skeletal and biological maturity of children. Delayed or increased bone age is a serious concern for pediatricians, and needs to be accurately assessed in a bid to determine whether bone maturity is occurring at a rate consistent with chronological age. In this paper, we introduce a unified deep learning framework for bone age assessment using instance segmentation and ridge regression. The proposed approach consists of two integrated stages. In the first stage, we employ an image annotation and segmentation model to annotate and segment the hand from the radiographic image, followed by background removal. In the second stage, we design a regression neural network architecture composed of a pre-trained convolutional neural network for learning salient features from the segmented pediatric hand radiographs and a ridge regression output layer for predicting the bone age. Experimental evaluation on a dataset of hand radiographs demonstrates the competitive performance of our approach in comparison with existing deep learning based methods for bone age assessment.