# Towards Automated and Marker-less Parkinson Disease Assessment: Predicting UPDRS Scores using Sit-stand videos

arXiv: https://arxiv.org/abs/2104.04650 · HTML: https://mlsanity.com/paper/2104.04650/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 11 of its 23 references that are in the map.
- First posted on arXiv 10 Apr 2021.

## Builds on (most cited first, 11 of 11)

- [UMAP: Uniform Manifold Approximation and Projection for Dimension Reduction](https://mlsanity.com/paper/1802.03426/) (2018)
- [Spatial Temporal Graph Convolutional Networks for Skeleton-Based Action Recognition](https://mlsanity.com/paper/1801.07455/) (2018)
- [When Does Label Smoothing Help?](https://mlsanity.com/paper/1906.02629/) (2019)
- [Regularizing Neural Networks by Penalizing Confident Output Distributions](https://mlsanity.com/paper/1701.06548/) (2017)
- [An Attention Enhanced Graph Convolutional LSTM Network for Skeleton-Based Action Recognition](https://mlsanity.com/paper/1902.09130/) (2019)
- [Co-occurrence Feature Learning from Skeleton Data for Action Recognition and Detection with Hierarchical Aggregation](https://mlsanity.com/paper/1804.06055/) (2018)
- [Interpretable 3D Human Action Analysis with Temporal Convolutional Networks](https://mlsanity.com/paper/1704.04516/) (2017)
- [Skeleton-Based Human Action Recognition with Global Context-Aware Attention LSTM Networks](https://mlsanity.com/paper/1707.05740/) (2017)
- [SkeleMotion: A New Representation of Skeleton Joint Sequences Based on Motion Information for 3D Action Recognition](https://mlsanity.com/paper/1907.13025/) (2019)
- [Real-time 2D Multi-Person Pose Estimation on CPU: Lightweight OpenPose](https://mlsanity.com/paper/1811.12004/) (2018)
- [SSHFD: Single Shot Human Fall Detection with Occluded Joints Resilience](https://mlsanity.com/paper/2004.00797/) (2020)

## Built on by (most cited first, 2 of 2)

- [Benchmarking Skeleton-based Motion Encoder Models for Clinical Applications: Estimating Parkinson's Disease Severity in Walking Sequences](https://mlsanity.com/paper/2405.17817/) (2024)
- [Your Turn: At Home Turning Angle Estimation for Parkinson's Disease Severity Assessment](https://mlsanity.com/paper/2408.08182/) (2024)

## Abstract (arXiv)

This paper presents a novel deep learning enabled, video based analysis framework for assessing the Unified Parkinsons Disease Rating Scale (UPDRS) that can be used in the clinic or at home. We report results from comparing the performance of the framework to that of trained clinicians on a population of 32 Parkinsons disease (PD) patients. In-person clinical assessments by trained neurologists are used as the ground truth for training our framework and for comparing the performance. We find that the standard sit-to-stand activity can be used to evaluate the UPDRS sub-scores of bradykinesia (BRADY) and posture instability and gait disorders (PIGD). For BRADY we find F1-scores of 0.75 using our framework compared to 0.50 for the video based rater clinicians, while for PIGD we find 0.78 for the framework and 0.45 for the video based rater clinicians. We believe our proposed framework has potential to provide clinically acceptable end points of PD in greater granularity without imposing burdens on patients and clinicians, which empowers a variety of use cases such as passive tracking of PD progression in spaces such as nursing homes, in-home self-assessment, and enhanced tele-medicine.