# TB-Net: A Tailored, Self-Attention Deep Convolutional Neural Network Design for Detection of Tuberculosis Cases from Chest X-ray Images

arXiv: https://arxiv.org/abs/2104.03165 · HTML: https://mlsanity.com/paper/2104.03165/

## Key facts

- Cited by 8 papers in the map (data through 14 Oct 2026).
- Builds on 20 of its 51 references that are in the map.
- First posted on arXiv 6 Apr 2021.

## Builds on (most cited first, 20 of 20)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [Learning Transferable Architectures for Scalable Image Recognition](https://mlsanity.com/paper/1707.07012/) (2017)
- [SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and <0.5MB model size](https://mlsanity.com/paper/1602.07360/) (2016)
- [CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning](https://mlsanity.com/paper/1711.05225/) (2017)
- [COVID-Net: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-Ray Images](https://mlsanity.com/paper/2003.09871/) (2020)
- [Reliable Tuberculosis Detection using Chest X-ray with Deep Learning, Segmentation and Visualization](https://mlsanity.com/paper/2007.14895/) (2020)
- [COVIDNet-CT: A Tailored Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest CT Images](https://mlsanity.com/paper/2009.05383/) (2020)
- [Do Explanations Reflect Decisions? A Machine-centric Strategy to Quantify the Performance of Explainability Algorithms](https://mlsanity.com/paper/1910.07387/) (2019)
- [NetScore: Towards Universal Metrics for Large-scale Performance Analysis of Deep Neural Networks for Practical On-Device Edge Usage](https://mlsanity.com/paper/1806.05512/) (2018)
- [COVID-Net CT-2: Enhanced Deep Neural Networks for Detection of COVID-19 from Chest CT Images Through Bigger, More Diverse Learning](https://mlsanity.com/paper/2101.07433/) (2021)
- [FermiNets: Learning generative machines to generate efficient neural networks via generative synthesis](https://mlsanity.com/paper/1809.05989/) (2018)
- [COVIDx-US -- An open-access benchmark dataset of ultrasound imaging data for AI-driven COVID-19 analytics](https://mlsanity.com/paper/2103.10003/) (2021)
- [TinySpeech: Attention Condensers for Deep Speech Recognition Neural Networks on Edge Devices](https://mlsanity.com/paper/2008.04245/) (2020)
- [COVID-Net S: Towards computer-aided severity assessment via training and validation of deep neural networks for geographic extent and opacity extent scoring of chest X-rays for SARS-CoV-2 lung disease severity](https://mlsanity.com/paper/2005.12855/) (2020)
- [AttendNets: Tiny Deep Image Recognition Neural Networks for the Edge via Visual Attention Condensers](https://mlsanity.com/paper/2009.14385/) (2020)

## Built on by (most cited first, 8 of 8)

- [COVID-Net CXR-2: An Enhanced Deep Convolutional Neural Network Design for Detection of COVID-19 Cases from Chest X-ray Images](https://mlsanity.com/paper/2105.06640/) (2021)
- [COVID-Net CXR-S: Deep Convolutional Neural Network for Severity Assessment of COVID-19 Cases from Chest X-ray Images](https://mlsanity.com/paper/2105.00256/) (2021)
- [MEDUSA: Multi-scale Encoder-Decoder Self-Attention Deep Neural Network Architecture for Medical Image Analysis](https://mlsanity.com/paper/2110.06063/) (2021)
- [Faster Attention Is What You Need: A Fast Self-Attention Neural Network Backbone Architecture for the Edge via Double-Condensing Attention Condensers](https://mlsanity.com/paper/2208.06980/) (2022)
- [A Lightweight, Rapid and Efficient Deep Convolutional Network for Chest X-Ray Tuberculosis Detection](https://mlsanity.com/paper/2309.02140/) (2023)
- [Zero-Shot Pediatric Tuberculosis Detection in Chest X-Rays using Self-Supervised Learning](https://mlsanity.com/paper/2402.14741/) (2024)
- [Empowering Tuberculosis Screening with Explainable Self-Supervised Deep Neural Networks](https://mlsanity.com/paper/2406.13750/) (2024)
- [An Explainable Hybrid AI Framework for Enhanced Tuberculosis and Symptom Detection](https://mlsanity.com/paper/2510.18819/) (2025)

## Abstract (arXiv)

Tuberculosis (TB) remains a global health problem, and is the leading cause of death from an infectious disease. A crucial step in the treatment of tuberculosis is screening high risk populations and the early detection of the disease, with chest x-ray (CXR) imaging being the most widely-used imaging modality. As such, there has been significant recent interest in artificial intelligence-based TB screening solutions for use in resource-limited scenarios where there is a lack of trained healthcare workers with expertise in CXR interpretation. Motivated by this pressing need and the recent recommendation by the World Health Organization (WHO) for the use of computer-aided diagnosis of TB, we introduce TB-Net, a self-attention deep convolutional neural network tailored for TB case screening. More specifically, we leveraged machine-driven design exploration to build a highly customized deep neural network architecture with attention condensers. We conducted an explainability-driven performance validation process to validate TB-Net's decision-making behaviour. Experiments on CXR data from a multi-national patient cohort showed that the proposed TB-Net is able to achieve accuracy/sensitivity/specificity of 99.86%/100.0%/99.71%. Radiologist validation was conducted on select cases by two board-certified radiologists with over 10 and 19 years of experience, respectively, and showed consistency between radiologist interpretation and critical factors leveraged by TB-Net for TB case detection for the case where radiologists identified anomalies. While not a production-ready solution, we hope that the open-source release of TB-Net as part of the COVID-Net initiative will support researchers, clinicians, and citizen data scientists in advancing this field in the fight against this global public health crisis.
