# CNN-based Cardiac Motion Extraction to Generate Deformable Geometric Left Ventricle Myocardial Models from Cine MRI

arXiv: https://arxiv.org/abs/2103.16695 · HTML: https://mlsanity.com/paper/2103.16695/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 4 of its 21 references that are in the map.
- First posted on arXiv 30 Mar 2021.

## Builds on (most cited first, 4 of 4)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [VoxelMorph: A Learning Framework for Deformable Medical Image Registration](https://mlsanity.com/paper/1809.05231/) (2018)
- [Unsupervised Learning of Probabilistic Diffeomorphic Registration for Images and Surfaces](https://mlsanity.com/paper/1903.03545/) (2019)
- [Deep learning cardiac motion analysis for human survival prediction](https://mlsanity.com/paper/1810.03382/) (2018)

## Built on by (most cited first, 3 of 3)

- [Explicit Differentiable Slicing and Global Deformation for Cardiac Mesh Reconstruction](https://mlsanity.com/paper/2409.02070/) (2024)
- [From Pixels to Polygons: A Survey of Deep Learning Approaches for Medical Image-to-Mesh Reconstruction](https://mlsanity.com/paper/2505.03599/) (2025)
- [CardioMorphNet: Cardiac Motion Prediction Using a Shape-Guided Bayesian Recurrent Deep Network](https://mlsanity.com/paper/2508.20734/) (2025)

## Abstract (arXiv)

Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images to reconstruct patient-specific geometric models of the LV myocardium. With the advent of deep learning, accurate segmentation of cardiac chambers from cine cardiac MR images and unsupervised learning for image registration for cardiac motion estimation on a large number of image datasets is attainable. Here, we propose a deep leaning-based framework for the development of patient-specific geometric models of LV myocardium from cine cardiac MR images, using the Automated Cardiac Diagnosis Challenge (ACDC) dataset. We use the deformation field estimated from the VoxelMorph-based convolutional neural network (CNN) to propagate the isosurface mesh and volume mesh of the end-diastole (ED) frame to the subsequent frames of the cardiac cycle. We assess the CNN-based propagated models against segmented models at each cardiac phase, as well as models propagated using another traditional nonrigid image registration technique.