# Spatially Dependent U-Nets: Highly Accurate Architectures for Medical Imaging Segmentation

arXiv: https://arxiv.org/abs/2103.11713 · HTML: https://mlsanity.com/paper/2103.11713/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 9 of its 17 references that are in the map.
- First posted on arXiv 22 Mar 2021.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Learning Phrase Representations using RNN Encoder-Decoder for Statistical Machine Translation](https://mlsanity.com/paper/1406.1078/) (2014)
- [UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation](https://mlsanity.com/paper/1912.05074/) (2019)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [No New-Net](https://mlsanity.com/paper/1809.10483/) (2018)
- [SegAN: Adversarial Network with Multi-scale L1 Loss for Medical Image Segmentation](https://mlsanity.com/paper/1706.01805/) (2017)
- [Spatial Dependency Networks: Neural Layers for Improved Generative Image Modeling](https://mlsanity.com/paper/2103.08877/) (2021)

## Built on by (most cited first, 1 of 1)

- [Rethinking Handwritten Character Recognition](https://mlsanity.com/paper/2609.10572/) (2026)

## Abstract (arXiv)

In clinical practice, regions of interest in medical imaging often need to be identified through a process of precise image segmentation. The quality of this image segmentation step critically affects the subsequent clinical assessment of the patient status. To enable high accuracy, automatic image segmentation, we introduce a novel deep neural network architecture that exploits the inherent spatial coherence of anatomical structures and is well equipped to capture long-range spatial dependencies in the segmented pixel/voxel space. In contrast to the state-of-the-art solutions based on convolutional layers, our approach leverages on recently introduced spatial dependency layers that have an unbounded receptive field and explicitly model the inductive bias of spatial coherence. Our method performs favourably to commonly used U-Net and U-Net++ architectures as demonstrated by improved Dice and Jaccardscore in three different medical segmentation tasks: nuclei segmentation in microscopy images, polyp segmentation in colonoscopy videos, and liver segmentation in abdominal CT scans.