# Automated liver tissues delineation techniques: A systematic survey on machine learning current trends and future orientations

arXiv: https://arxiv.org/abs/2103.06384 · HTML: https://mlsanity.com/paper/2103.06384/

## Key facts

- Cited by 3 papers in the map (data through 7 Oct 2026).
- Builds on 46 of its 195 references that are in the map.
- First posted on arXiv 10 Mar 2021.

## Builds on (most cited first, 30 of 46)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [3D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotation](https://mlsanity.com/paper/1606.06650/) (2016)
- [Holistically-Nested Edge Detection](https://mlsanity.com/paper/1504.06375/) (2015)
- [UNet++: Redesigning Skip Connections to Exploit Multiscale Features in Image Segmentation](https://mlsanity.com/paper/1912.05074/) (2019)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [A large annotated medical image dataset for the development and evaluation of segmentation algorithms](https://mlsanity.com/paper/1902.09063/) (2019)
- [CHAOS Challenge -- Combined (CT-MR) Healthy Abdominal Organ Segmentation](https://mlsanity.com/paper/2001.06535/) (2020)
- [Efficient Multi-Scale 3D CNN with Fully Connected CRF for Accurate Brain Lesion Segmentation](https://mlsanity.com/paper/1603.05959/) (2016)
- [Models Genesis: Generic Autodidactic Models for 3D Medical Image Analysis](https://mlsanity.com/paper/1908.06912/) (2019)
- [Explainable deep learning models in medical image analysis](https://mlsanity.com/paper/2005.13799/) (2020)
- [Prior-aware Neural Network for Partially-Supervised Multi-Organ Segmentation](https://mlsanity.com/paper/1904.06346/) (2019)
- [Multi-organ Segmentation over Partially Labeled Datasets with Multi-scale Feature Abstraction](https://mlsanity.com/paper/2001.00208/) (2020)
- [A New 2.5D Representation for Lymph Node Detection using Random Sets of Deep Convolutional Neural Network Observations](https://mlsanity.com/paper/1406.2639/) (2014)
- [Unsupervised Domain Adaptation via Disentangled Representations: Application to Cross-Modality Liver Segmentation](https://mlsanity.com/paper/1907.13590/) (2019)
- [Task Driven Generative Modeling for Unsupervised Domain Adaptation: Application to X-ray Image Segmentation](https://mlsanity.com/paper/1806.07201/) (2018)
- [Abdominal multi-organ segmentation with organ-attention networks and statistical fusion](https://mlsanity.com/paper/1804.08414/) (2018)
- [NiftyNet: a deep-learning platform for medical imaging](https://mlsanity.com/paper/1709.03485/) (2017)
- [3D Deeply Supervised Network for Automatic Liver Segmentation from CT Volumes](https://mlsanity.com/paper/1607.00582/) (2016)
- [Automatic Liver and Lesion Segmentation in CT Using Cascaded Fully Convolutional Neural Networks and 3D Conditional Random Fields](https://mlsanity.com/paper/1610.02177/) (2016)
- [RA-UNet: A hybrid deep attention-aware network to extract liver and tumor in CT scans](https://mlsanity.com/paper/1811.01328/) (2018)
- [Closing the Gap between Deep and Conventional Image Registration using Probabilistic Dense Displacement Networks](https://mlsanity.com/paper/1907.10931/) (2019)
- [3D Anisotropic Hybrid Network: Transferring Convolutional Features from 2D Images to 3D Anisotropic Volumes](https://mlsanity.com/paper/1711.08580/) (2017)
- [Simulation of hyperelastic materials in real-time using Deep Learning](https://mlsanity.com/paper/1904.06197/) (2019)
- [An application of cascaded 3D fully convolutional networks for medical image segmentation](https://mlsanity.com/paper/1803.05431/) (2018)
- [Volumetric Attention for 3D Medical Image Segmentation and Detection](https://mlsanity.com/paper/2004.01997/) (2020)
- [Automatic Liver and Tumor Segmentation of CT and MRI Volumes using Cascaded Fully Convolutional Neural Networks](https://mlsanity.com/paper/1702.05970/) (2017)
- [Modified U-Net (mU-Net) with Incorporation of Object-Dependent High Level Features for Improved Liver and Liver-Tumor Segmentation in CT Images](https://mlsanity.com/paper/1911.00140/) (2019)
- [One Network to Segment Them All: A General, Lightweight System for Accurate 3D Medical Image Segmentation](https://mlsanity.com/paper/1911.01764/) (2019)
- [Automatic Liver Lesion Segmentation Using A Deep Convolutional Neural Network Method](https://mlsanity.com/paper/1704.07239/) (2017)
- [Liver lesion segmentation informed by joint liver segmentation](https://mlsanity.com/paper/1707.07734/) (2017)

## Built on by (most cited first, 3 of 3)

- [Federated Learning for Computer Vision](https://mlsanity.com/paper/2308.13558/) (2023)
- [Deep Transfer Learning for Kidney Cancer Diagnosis](https://mlsanity.com/paper/2408.04318/) (2024)
- [AI Radiologist: Revolutionizing Liver Tissue Segmentation with Convolutional Neural Networks and a Clinician-Friendly GUI](https://mlsanity.com/paper/2406.07688/) (2024)

## Abstract (arXiv)

Machine learning and computer vision techniques have grown rapidly in recent years due to their automation, suitability, and ability to generate astounding results. Hence, in this paper, we survey the key studies that are published between 2014 and 2022, showcasing the different machine learning algorithms researchers have used to segment the liver, hepatic tumors, and hepatic-vasculature structures. We divide the surveyed studies based on the tissue of interest (hepatic-parenchyma, hepatic-tumors, or hepatic-vessels), highlighting the studies that tackle more than one task simultaneously. Additionally, the machine learning algorithms are classified as either supervised or unsupervised, and they are further partitioned if the amount of work that falls under a certain scheme is significant. Moreover, different datasets and challenges found in literature and websites containing masks of the aforementioned tissues are thoroughly discussed, highlighting the organizers' original contributions and those of other researchers. Also, the metrics used excessively in literature are mentioned in our review, stressing their relevance to the task at hand. Finally, critical challenges and future directions are emphasized for innovative researchers to tackle, exposing gaps that need addressing, such as the scarcity of many studies on the vessels' segmentation challenge and why their absence needs to be dealt with sooner than later.