# COVID-19 identification from volumetric chest CT scans using a progressively resized 3D-CNN incorporating segmentation, augmentation, and class-rebalancing

arXiv: https://arxiv.org/abs/2102.06169 · HTML: https://mlsanity.com/paper/2102.06169/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 47 of its 131 references that are in the map.
- First posted on arXiv 11 Feb 2021.

## Builds on (most cited first, 30 of 47)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift](https://mlsanity.com/paper/1502.03167/) (2015)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [Going Deeper with Convolutions](https://mlsanity.com/paper/1409.4842/) (2014)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [Xception: Deep Learning with Depthwise Separable Convolutions](https://mlsanity.com/paper/1610.02357/) (2016)
- [Inception-v4, Inception-ResNet and the Impact of Residual Connections on Learning](https://mlsanity.com/paper/1602.07261/) (2016)
- [ShuffleNet: An Extremely Efficient Convolutional Neural Network for Mobile Devices](https://mlsanity.com/paper/1707.01083/) (2017)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [Learning Transferable Architectures for Scalable Image Recognition](https://mlsanity.com/paper/1707.07012/) (2017)
- [SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and <0.5MB model size](https://mlsanity.com/paper/1602.07360/) (2016)
- [An overview of gradient descent optimization algorithms](https://mlsanity.com/paper/1609.04747/) (2016)
- [On the Convergence of Adam and Beyond](https://mlsanity.com/paper/1904.09237/) (2019)
- [Efficient Neural Architecture Search via Parameter Sharing](https://mlsanity.com/paper/1802.03268/) (2018)
- [Empirical Evaluation of Rectified Activations in Convolutional Network](https://mlsanity.com/paper/1505.00853/) (2015)
- [CheXNet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning](https://mlsanity.com/paper/1711.05225/) (2017)
- [Not-so-supervised: a survey of semi-supervised, multi-instance, and transfer learning in medical image analysis](https://mlsanity.com/paper/1804.06353/) (2018)
- [TieNet: Text-Image Embedding Network for Common Thorax Disease Classification and Reporting in Chest X-rays](https://mlsanity.com/paper/1801.04334/) (2018)
- [MosMedData: Chest CT Scans With COVID-19 Related Findings Dataset](https://mlsanity.com/paper/2005.06465/) (2020)
- [Deep Learning in Medical Image Registration: A Review](https://mlsanity.com/paper/1912.12318/) (2019)
- [COVID-CT-Dataset: A CT Scan Dataset about COVID-19](https://mlsanity.com/paper/2003.13865/) (2020)
- [Covid-19: Automatic detection from X-Ray images utilizing Transfer Learning with Convolutional Neural Networks](https://mlsanity.com/paper/2003.11617/) (2020)
- [Automatic Detection of Coronavirus Disease (COVID-19) Using X-ray Images and Deep Convolutional Neural Networks](https://mlsanity.com/paper/2003.10849/) (2020)
- [3D Deep Learning on Medical Images: A Review](https://mlsanity.com/paper/2004.00218/) (2020)
- [CoroNet: A deep neural network for detection and diagnosis of COVID-19 from chest x-ray images](https://mlsanity.com/paper/2004.04931/) (2020)

## Built on by (most cited first, 2 of 2)

- [Acute Lymphoblastic Leukemia Detection from Microscopic Images Using Weighted Ensemble of Convolutional Neural Networks](https://mlsanity.com/paper/2105.03995/) (2021)
- [INSIGHT: Explainable Weakly-Supervised Medical Image Analysis](https://mlsanity.com/paper/2412.02012/) (2024)

## Abstract (arXiv)

The novel COVID-19 is a global pandemic disease overgrowing worldwide. Computer-aided screening tools with greater sensitivity is imperative for disease diagnosis and prognosis as early as possible. It also can be a helpful tool in triage for testing and clinical supervision of COVID-19 patients. However, designing such an automated tool from non-invasive radiographic images is challenging as many manually annotated datasets are not publicly available yet, which is the essential core requirement of supervised learning schemes. This article proposes a 3D Convolutional Neural Network (CNN)-based classification approach considering both the inter- and intra-slice spatial voxel information. The proposed system is trained in an end-to-end manner on the 3D patches from the whole volumetric CT images to enlarge the number of training samples, performing the ablation studies on patch size determination. We integrate progressive resizing, segmentation, augmentations, and class-rebalancing to our 3D network. The segmentation is a critical prerequisite step for COVID-19 diagnosis enabling the classifier to learn prominent lung features while excluding the outer lung regions of the CT scans. We evaluate all the extensive experiments on a publicly available dataset, named MosMed, having binary- and multi-class chest CT image partitions. Our experimental results are very encouraging, yielding areas under the ROC curve of 0.914 and 0.893 for the binary- and multi-class tasks, respectively, applying 5-fold cross-validations. Our method's promising results delegate it as a favorable aiding tool for clinical practitioners and radiologists to assess COVID-19.
