# Inheritance-guided Hierarchical Assignment for Clinical Automatic Diagnosis

arXiv: https://arxiv.org/abs/2101.11374 · HTML: https://mlsanity.com/paper/2101.11374/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 11 of its 25 references that are in the map.
- First posted on arXiv 27 Jan 2021.

## Builds on (most cited first, 11 of 11)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Semi-Supervised Classification with Graph Convolutional Networks](https://mlsanity.com/paper/1609.02907/) (2016)
- [Efficient Estimation of Word Representations in Vector Space](https://mlsanity.com/paper/1301.3781/) (2013)
- [Graph Convolutional Networks for Text Classification](https://mlsanity.com/paper/1809.05679/) (2018)
- [Explainable Prediction of Medical Codes from Clinical Text](https://mlsanity.com/paper/1802.05695/) (2018)
- [ICD Coding from Clinical Text Using Multi-Filter Residual Convolutional Neural Network](https://mlsanity.com/paper/1912.00862/) (2019)
- [Graph Convolutional Encoders for Syntax-aware Neural Machine Translation](https://mlsanity.com/paper/1704.04675/) (2017)
- [Joint Embedding of Words and Labels for Text Classification](https://mlsanity.com/paper/1805.04174/) (2018)
- [Multi-Label Classification of Patient Notes a Case Study on ICD Code Assignment](https://mlsanity.com/paper/1709.09587/) (2017)
- [Towards Automated ICD Coding Using Deep Learning](https://mlsanity.com/paper/1711.04075/) (2017)
- [Condensed Memory Networks for Clinical Diagnostic Inferencing](https://mlsanity.com/paper/1612.01848/) (2016)

## Built on by (most cited first, 2 of 2)

- [Trustworthy Graph Neural Networks: Aspects, Methods and Trends](https://mlsanity.com/paper/2205.07424/) (2022)
- [Structure-free Graph Condensation: From Large-scale Graphs to Condensed Graph-free Data](https://mlsanity.com/paper/2306.02664/) (2023)

## Abstract (arXiv)

Clinical diagnosis, which aims to assign diagnosis codes for a patient based on the clinical note, plays an essential role in clinical decision-making. Considering that manual diagnosis could be error-prone and time-consuming, many intelligent approaches based on clinical text mining have been proposed to perform automatic diagnosis. However, these methods may not achieve satisfactory results due to the following challenges. First, most of the diagnosis codes are rare, and the distribution is extremely unbalanced. Second, existing methods are challenging to capture the correlation between diagnosis codes. Third, the lengthy clinical note leads to the excessive dispersion of key information related to codes. To tackle these challenges, we propose a novel framework to combine the inheritance-guided hierarchical assignment and co-occurrence graph propagation for clinical automatic diagnosis. Specifically, we propose a hierarchical joint prediction strategy to address the challenge of unbalanced codes distribution. Then, we utilize graph convolutional neural networks to obtain the correlation and semantic representations of medical ontology. Furthermore, we introduce multi attention mechanisms to extract crucial information. Finally, extensive experiments on MIMIC-III dataset clearly validate the effectiveness of our method.