# Temporal Spatial-Adaptive Interpolation with Deformable Refinement for Electron Microscopic Images

arXiv: https://arxiv.org/abs/2101.06771 · HTML: https://mlsanity.com/paper/2101.06771/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 19 of its 29 references that are in the map.
- First posted on arXiv 17 Jan 2021.

## Builds on (most cited first, 19 of 19)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Perceptual Losses for Real-Time Style Transfer and Super-Resolution](https://mlsanity.com/paper/1603.08155/) (2016)
- [Deformable Convolutional Networks](https://mlsanity.com/paper/1703.06211/) (2017)
- [FlowNet: Learning Optical Flow with Convolutional Networks](https://mlsanity.com/paper/1504.06852/) (2015)
- [FlowNet 2.0: Evolution of Optical Flow Estimation with Deep Networks](https://mlsanity.com/paper/1612.01925/) (2016)
- [Deformable ConvNets v2: More Deformable, Better Results](https://mlsanity.com/paper/1811.11168/) (2018)
- [Video Enhancement with Task-Oriented Flow](https://mlsanity.com/paper/1711.09078/) (2017)
- [EDVR: Video Restoration with Enhanced Deformable Convolutional Networks](https://mlsanity.com/paper/1905.02716/) (2019)
- [Depth-Aware Video Frame Interpolation](https://mlsanity.com/paper/1904.00830/) (2019)
- [Video Frame Interpolation via Adaptive Separable Convolution](https://mlsanity.com/paper/1708.01692/) (2017)
- [Video Frame Synthesis using Deep Voxel Flow](https://mlsanity.com/paper/1702.02463/) (2017)
- [Frame-Recurrent Video Super-Resolution](https://mlsanity.com/paper/1801.04590/) (2018)
- [Video Frame Interpolation via Adaptive Convolution](https://mlsanity.com/paper/1703.07514/) (2017)
- [Context-aware Synthesis for Video Frame Interpolation](https://mlsanity.com/paper/1803.10967/) (2018)
- [MEMC-Net: Motion Estimation and Motion Compensation Driven Neural Network for Video Interpolation and Enhancement](https://mlsanity.com/paper/1810.08768/) (2018)
- [Learning Image Matching by Simply Watching Video](https://mlsanity.com/paper/1603.06041/) (2016)
- [Inter-slice image augmentation based on frame interpolation for boosting medical image segmentation accuracy](https://mlsanity.com/paper/2001.11698/) (2020)

## Built on by (most cited first, 1 of 1)

- [VEMamba: Efficient Isotropic Reconstruction of Volume Electron Microscopy with Axial-Lateral Consistent Mamba](https://mlsanity.com/paper/2603.00887/) (2026)

## Abstract (arXiv)

Recently, flow-based methods have achieved promising success in video frame interpolation. However, electron microscopic (EM) images suffer from unstable image quality, low PSNR, and disorderly deformation. Existing flow-based interpolation methods cannot precisely compute optical flow for EM images since only predicting each position's unique offset. To overcome these problems, we propose a novel interpolation framework for EM images that progressively synthesizes interpolated features in a coarse-to-fine manner. First, we extract missing intermediate features by the proposed temporal spatial-adaptive (TSA) interpolation module. The TSA interpolation module aggregates temporal contexts and then adaptively samples the spatial-related features with the proposed residual spatial adaptive block. Second, we introduce a stacked deformable refinement block (SDRB) further enhance the reconstruction quality, which is aware of the matching positions and relevant features from input frames with the feedback mechanism. Experimental results demonstrate the superior performance of our approach compared to previous works, both quantitatively and qualitatively.