# Competition-based control of the false discovery proportion

arXiv: https://arxiv.org/abs/2011.11939 · HTML: https://mlsanity.com/paper/2011.11939/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 24 Nov 2020.

## Built on by (most cited first, 3 of 3)

- [Error-based Knockoffs Inference for Controlled Feature Selection](https://mlsanity.com/paper/2203.04483/) (2022)
- [CatNet: Controlling the False Discovery Rate in LSTM with SHAP Feature Importance and Gaussian Mirrors](https://mlsanity.com/paper/2411.16666/) (2024)
- [Model-Agnostic FDR Control via Group Gaussian Mirror and Permutation SHAP](https://mlsanity.com/paper/2608.00989/) (2026)

## Abstract (arXiv)

Recently, Barber and Cand`es laid the theoretical foundation for a general framework for false discovery rate (FDR) control based on the notion of "knockoffs." A closely related FDR control methodology has long been employed in the analysis of mass spectrometry data, referred to there as "target-decoy competition" (TDC). However, any approach that aims to control the FDR, which is defined as the expected value of the false discovery proportion (FDP), suffers from a problem. Specifically, even when successfully controlling the FDR at level α, the FDP in the list of discoveries can significantly exceed α. We offer FDP-SD, a new procedure that rigorously controls the FDP in the competition (knockoff / TDC) setup by guaranteeing that the FDP is bounded by α at any desired confidence level. Compared with the just-published general framework of Katsevich and Ramdas, FDP-SD generally delivers more power and often substantially so in simulated as well as real data.
