# Quasiconformal model with CNN features for large deformation image registration

arXiv: https://arxiv.org/abs/2011.00731 · HTML: https://mlsanity.com/paper/2011.00731/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 30 Oct 2020.

## Built on by (most cited first, 3 of 3)

- [A unifying framework for n-dimensional quasi-conformal mappings](https://mlsanity.com/paper/2110.10437/) (2021)
- [A Deep Learning Framework for Diffeomorphic Mapping Problems via Quasi-conformal Geometry applied to Imaging](https://mlsanity.com/paper/2110.10580/) (2021)
- [Automatic Landmark Detection and Registration of Brain Cortical Surfaces via Quasi-Conformal Geometry and Convolutional Neural Networks](https://mlsanity.com/paper/2208.07010/) (2022)

## Abstract (arXiv)

Image registration has been widely studied over the past several decades, with numerous applications in science, engineering and medicine. Most of the conventional mathematical models for large deformation image registration rely on prescribed landmarks, which usually require tedious manual labeling and are prone to error. In recent years, there has been a surge of interest in the use of machine learning for image registration. In this paper, we develop a novel method for large deformation image registration by a fusion of quasiconformal theory and convolutional neural network (CNN). More specifically, we propose a quasiconformal energy model with a novel fidelity term that incorporates the features extracted using a pre-trained CNN, thereby allowing us to obtain meaningful registration results without any guidance of prescribed landmarks. Moreover, unlike many prior image registration methods, the bijectivity of our method is guaranteed by quasiconformal theory. Experimental results are presented to demonstrate the effectiveness of the proposed method. More broadly, our work sheds light on how rigorous mathematical theories and practical machine learning approaches can be integrated for developing computational methods with improved performance.