# DeepCSR: A 3D Deep Learning Approach for Cortical Surface Reconstruction

arXiv: https://arxiv.org/abs/2010.11423 · HTML: https://mlsanity.com/paper/2010.11423/

## Key facts

- Cited by 27 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 22 Oct 2020.

## Built on by (most cited first, 27 of 27)

- [Vox2Cortex: Fast Explicit Reconstruction of Cortical Surfaces from 3D MRI Scans with Geometric Deep Neural Networks](https://mlsanity.com/paper/2203.09446/) (2022)
- [CortexODE: Learning Cortical Surface Reconstruction by Neural ODEs](https://mlsanity.com/paper/2202.08329/) (2022)
- [CorticalFlow++: Boosting Cortical Surface Reconstruction Accuracy, Regularity, and Interoperability](https://mlsanity.com/paper/2206.06598/) (2022)
- [Diffeomorphic Mesh Deformation via Efficient Optimal Transport for Cortical Surface Reconstruction](https://mlsanity.com/paper/2305.17555/) (2023)
- [Recon-all-clinical: Cortical surface reconstruction and analysis of heterogeneous clinical brain MRI](https://mlsanity.com/paper/2409.03889/) (2024)
- [Cortical analysis of heterogeneous clinical brain MRI scans for large-scale neuroimaging studies](https://mlsanity.com/paper/2305.01827/) (2023)
- [End-to-End 4D Heart Mesh Recovery Across Full-Stack and Sparse Cardiac MRI](https://mlsanity.com/paper/2509.12090/) (2025)
- [CorticalFlow: A Diffeomorphic Mesh Deformation Module for Cortical Surface Reconstruction](https://mlsanity.com/paper/2206.02374/) (2022)
- [Hybrid-CSR: Coupling Explicit and Implicit Shape Representation for Cortical Surface Reconstruction](https://mlsanity.com/paper/2307.12299/) (2023)
- [From Pixels to Polygons: A Survey of Deep Learning Approaches for Medical Image-to-Mesh Reconstruction](https://mlsanity.com/paper/2505.03599/) (2025)
- [MongeNet: Efficient Sampler for Geometric Deep Learning](https://mlsanity.com/paper/2104.14554/) (2021)
- [SurfNN: Joint Reconstruction of Multiple Cortical Surfaces from Magnetic Resonance Images](https://mlsanity.com/paper/2303.02922/) (2023)
- [From Low Field to High Value: Robust Cortical Mapping from Low-Field MRI](https://mlsanity.com/paper/2505.12228/) (2025)
- [From 2D to 3D, Deep Learning-based Shape Reconstruction in Magnetic Resonance Imaging: A Review](https://mlsanity.com/paper/2510.01296/) (2025)
- [Joint Reconstruction and Parcellation of Cortical Surfaces](https://mlsanity.com/paper/2210.01772/) (2022)
- [End-to-end Cortical Surface Reconstruction from Clinical Magnetic Resonance Images](https://mlsanity.com/paper/2505.14017/) (2025)
- [Reconsider the Template Mesh in Deep Learning-based Mesh Reconstruction](https://mlsanity.com/paper/2505.15285/) (2025)
- [UNSURF: Uncertainty Quantification for Cortical Surface Reconstruction of Clinical Brain MRIs](https://mlsanity.com/paper/2506.00498/) (2025)
- [Improved Segmentation of Deep Sulci in Cortical Gray Matter Using a Deep Learning Framework Incorporating Laplace's Equation](https://mlsanity.com/paper/2303.00795/) (2023)
- [Reconstruction of Cortical Surfaces with Spherical Topology from Infant Brain MRI via Recurrent Deformation Learning](https://mlsanity.com/paper/2312.05986/) (2023)
- [V2C-Long: Longitudinal Cortex Reconstruction with Spatiotemporal Correspondence](https://mlsanity.com/paper/2402.17438/) (2024)
- [SimCortex: Collision-free Simultaneous Cortical Surfaces Reconstruction](https://mlsanity.com/paper/2507.06955/) (2025)
- [Template-Based Cortical Surface Reconstruction with Minimal Energy Deformation](https://mlsanity.com/paper/2509.14827/) (2025)
- [NC-Reg : Neural Cortical Maps for Rigid Registration](https://mlsanity.com/paper/2601.19042/) (2026)
- [KidMesh: Computational Mesh Reconstruction for Pediatric Congenital Hydronephrosis Using Deep Neural Networks](https://mlsanity.com/paper/2602.13299/) (2026)
- [AdamFlow: Adam-based Wasserstein Gradient Flows for Surface Registration in Medical Imaging](https://mlsanity.com/paper/2604.02290/) (2026)
- [Uncertainty-Aware Cortical Surface Reconstruction and Spherical Registration for Heterogeneous Brain MRI](https://mlsanity.com/paper/2610.16595/) (2026)

## Abstract (arXiv)

The study of neurodegenerative diseases relies on the reconstruction and analysis of the brain cortex from magnetic resonance imaging (MRI). Traditional frameworks for this task like FreeSurfer demand lengthy runtimes, while its accelerated variant FastSurfer still relies on a voxel-wise segmentation which is limited by its resolution to capture narrow continuous objects as cortical surfaces. Having these limitations in mind, we propose DeepCSR, a 3D deep learning framework for cortical surface reconstruction from MRI. Towards this end, we train a neural network model with hypercolumn features to predict implicit surface representations for points in a brain template space. After training, the cortical surface at a desired level of detail is obtained by evaluating surface representations at specific coordinates, and subsequently applying a topology correction algorithm and an isosurface extraction method. Thanks to the continuous nature of this approach and the efficacy of its hypercolumn features scheme, DeepCSR efficiently reconstructs cortical surfaces at high resolution capturing fine details in the cortical folding. Moreover, DeepCSR is as accurate, more precise, and faster than the widely used FreeSurfer toolbox and its deep learning powered variant FastSurfer on reconstructing cortical surfaces from MRI which should facilitate large-scale medical studies and new healthcare applications.