# Vocal markers from sustained phonation in Huntington's Disease

arXiv: https://arxiv.org/abs/2006.05365 · HTML: https://mlsanity.com/paper/2006.05365/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 9 Jun 2020.

## Built on by (most cited first, 1 of 1)

- [Shennong: a Python toolbox for audio speech features extraction](https://mlsanity.com/paper/2112.05555/) (2021)

## Abstract (arXiv)

Disease-modifying treatments are currently assessed in neurodegenerative diseases. Huntington's Disease represents a unique opportunity to design automatic sub-clinical markers, even in premanifest gene carriers. We investigated phonatory impairments as potential clinical markers and propose them for both diagnosis and gene carriers follow-up. We used two sets of features: Phonatory features and Modulation Power Spectrum Features. We found that phonation is not sufficient for the identification of sub-clinical disorders of premanifest gene carriers. According to our regression results, Phonatory features are suitable for the predictions of clinical performance in Huntington's Disease.