# Robustly Pre-trained Neural Model for Direct Temporal Relation Extraction

arXiv: https://arxiv.org/abs/2004.06216 · HTML: https://mlsanity.com/paper/2004.06216/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 13 Apr 2020.

## Built on by (most cited first, 3 of 3)

- [Pre-trained Language Models in Biomedical Domain: A Systematic Survey](https://mlsanity.com/paper/2110.05006/) (2021)
- [Deeper Clinical Document Understanding Using Relation Extraction](https://mlsanity.com/paper/2112.13259/) (2021)
- [GDLLM: A Global Distance-aware Modeling Approach Based on Large Language Models for Event Temporal Relation Extraction](https://mlsanity.com/paper/2508.20828/) (2025)

## Abstract (arXiv)

Background: Identifying relationships between clinical events and temporal expressions is a key challenge in meaningfully analyzing clinical text for use in advanced AI applications. While previous studies exist, the state-of-the-art performance has significant room for improvement. Methods: We studied several variants of BERT (Bidirectional Encoder Representations using Transformers) some involving clinical domain customization and the others involving improved architecture and/or training strategies. We evaluated these methods using a direct temporal relations dataset which is a semantically focused subset of the 2012 i2b2 temporal relations challenge dataset. Results: Our results show that RoBERTa, which employs better pre-training strategies including using 10x larger corpus, has improved overall F measure by 0.0864 absolute score (on the 1.00 scale) and thus reducing the error rate by 24% relative to the previous state-of-the-art performance achieved with an SVM (support vector machine) model. Conclusion: Modern contextual language modeling neural networks, pre-trained on a large corpus, achieve impressive performance even on highly-nuanced clinical temporal relation tasks.
