# PathVQA: 30000+ Questions for Medical Visual Question Answering

arXiv: https://arxiv.org/abs/2003.10286 · HTML: https://mlsanity.com/paper/2003.10286/

## Key facts

- Cited by 475 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 7 Mar 2020.

## Built on by (most cited first, 30 of 475)

- [Expanding Performance Boundaries of Open-Source Multimodal Models with Model, Data, and Test-Time Scaling](https://mlsanity.com/paper/2412.05271/) (2024)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [A Survey on Multimodal Large Language Models](https://mlsanity.com/paper/2306.13549/) (2023)
- [Cambrian-1: A Fully Open, Vision-Centric Exploration of Multimodal LLMs](https://mlsanity.com/paper/2406.16860/) (2024)
- [What matters when building vision-language models?](https://mlsanity.com/paper/2405.02246/) (2024)
- [Towards Generalist Biomedical AI](https://mlsanity.com/paper/2307.14334/) (2023)
- [Lingshu: A Generalist Foundation Model for Unified Multimodal Medical Understanding and Reasoning](https://mlsanity.com/paper/2506.07044/) (2025)
- [MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understanding](https://mlsanity.com/paper/2501.18362/) (2025)
- [NVILA: Efficient Frontier Visual Language Models](https://mlsanity.com/paper/2412.04468/) (2024)
- [HuatuoGPT-Vision, Towards Injecting Medical Visual Knowledge into Multimodal LLMs at Scale](https://mlsanity.com/paper/2406.19280/) (2024)
- [Quilt-1M: One Million Image-Text Pairs for Histopathology](https://mlsanity.com/paper/2306.11207/) (2023)
- [OmniMedVQA: A New Large-Scale Comprehensive Evaluation Benchmark for Medical LVLM](https://mlsanity.com/paper/2402.09181/) (2024)
- [Building and better understanding vision-language models: insights and future directions](https://mlsanity.com/paper/2408.12637/) (2024)
- [MedVLM-R1: Incentivizing Medical Reasoning Capability of Vision-Language Models (VLMs) via Reinforcement Learning](https://mlsanity.com/paper/2502.19634/) (2025)
- [A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethics](https://mlsanity.com/paper/2310.05694/) (2023)
- [MAmmoTH-VL: Eliciting Multimodal Reasoning with Instruction Tuning at Scale](https://mlsanity.com/paper/2412.05237/) (2024)
- [Vision-Language Models for Medical Report Generation and Visual Question Answering: A Review](https://mlsanity.com/paper/2403.02469/) (2024)
- [A Survey of Large Language Models in Medicine: Progress, Application, and Challenge](https://mlsanity.com/paper/2311.05112/) (2023)
- [Foundations and Trends in Multimodal Machine Learning: Principles, Challenges, and Open Questions](https://mlsanity.com/paper/2209.03430/) (2022)
- [Alita: Generalist Agent Enabling Scalable Agentic Reasoning with Minimal Predefinition and Maximal Self-Evolution](https://mlsanity.com/paper/2505.20286/) (2025)
- [HealthGPT: A Medical Large Vision-Language Model for Unifying Comprehension and Generation via Heterogeneous Knowledge Adaptation](https://mlsanity.com/paper/2502.09838/) (2025)
- [Baichuan-Omni-1.5 Technical Report](https://mlsanity.com/paper/2501.15368/) (2025)
- [MMedAgent: Learning to Use Medical Tools with Multi-modal Agent](https://mlsanity.com/paper/2407.02483/) (2024)
- [Mixture of Cluster-conditional LoRA Experts for Vision-language Instruction Tuning](https://mlsanity.com/paper/2312.12379/) (2023)
- [LongLLaVA: Scaling Multi-modal LLMs to 1000 Images Efficiently via a Hybrid Architecture](https://mlsanity.com/paper/2409.02889/) (2024)
- [GMAI-MMBench: A Comprehensive Multimodal Evaluation Benchmark Towards General Medical AI](https://mlsanity.com/paper/2408.03361/) (2024)
- [Medical Visual Question Answering: A Survey](https://mlsanity.com/paper/2111.10056/) (2021)
- [Advancing Multimodal Medical Capabilities of Gemini](https://mlsanity.com/paper/2405.03162/) (2024)
- [Quilt-LLaVA: Visual Instruction Tuning by Extracting Localized Narratives from Open-Source Histopathology Videos](https://mlsanity.com/paper/2312.04746/) (2023)
- [MedTrinity-25M: A Large-scale Multimodal Dataset with Multigranular Annotations for Medicine](https://mlsanity.com/paper/2408.02900/) (2024)

## Abstract (arXiv)

Is it possible to develop an "AI Pathologist" to pass the board-certified examination of the American Board of Pathology? To achieve this goal, the first step is to create a visual question answering (VQA) dataset where the AI agent is presented with a pathology image together with a question and is asked to give the correct answer. Our work makes the first attempt to build such a dataset. Different from creating general-domain VQA datasets where the images are widely accessible and there are many crowdsourcing workers available and capable of generating question-answer pairs, developing a medical VQA dataset is much more challenging. First, due to privacy concerns, pathology images are usually not publicly available. Second, only well-trained pathologists can understand pathology images, but they barely have time to help create datasets for AI research. To address these challenges, we resort to pathology textbooks and online digital libraries. We develop a semi-automated pipeline to extract pathology images and captions from textbooks and generate question-answer pairs from captions using natural language processing. We collect 32,799 open-ended questions from 4,998 pathology images where each question is manually checked to ensure correctness. To our best knowledge, this is the first dataset for pathology VQA. Our dataset will be released publicly to promote research in medical VQA.