# VerSe: A Vertebrae Labelling and Segmentation Benchmark for Multi-detector CT Images

arXiv: https://arxiv.org/abs/2001.09193 · HTML: https://mlsanity.com/paper/2001.09193/

## Key facts

- Cited by 111 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 24 Jan 2020.

## Built on by (most cited first, 30 of 111)

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- [Segment Anything Model for Medical Images?](https://mlsanity.com/paper/2304.14660/) (2023)
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- [A Systematic Collection of Medical Image Datasets for Deep Learning](https://mlsanity.com/paper/2106.12864/) (2021)
- [A Computed Tomography Vertebral Segmentation Dataset with Anatomical Variations and Multi-Vendor Scanner Data](https://mlsanity.com/paper/2103.06360/) (2021)
- [Detailed Annotations of Chest X-Rays via CT Projection for Report Understanding](https://mlsanity.com/paper/2210.03416/) (2022)
- [Accurate Fine-Grained Segmentation of Human Anatomy in Radiographs via Volumetric Pseudo-Labeling](https://mlsanity.com/paper/2306.03934/) (2023)
- [3DGR-CT: Sparse-View CT Reconstruction with a 3D Gaussian Representation](https://mlsanity.com/paper/2312.15676/) (2023)
- [Towards Unifying Anatomy Segmentation: Automated Generation of a Full-body CT Dataset via Knowledge Aggregation and Anatomical Guidelines](https://mlsanity.com/paper/2307.13375/) (2023)
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- [MIMO: A medical vision language model with visual referring multimodal input and pixel grounding multimodal output](https://mlsanity.com/paper/2510.10011/) (2025)
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- [BOSS: Bones, Organs and Skin Shape Model](https://mlsanity.com/paper/2303.04923/) (2023)
- [Panoptica -- instance-wise evaluation of 3D semantic and instance segmentation maps](https://mlsanity.com/paper/2312.02608/) (2023)
- [SAM Fewshot Finetuning for Anatomical Segmentation in Medical Images](https://mlsanity.com/paper/2407.04651/) (2024)
- [LesionLocator: Zero-Shot Universal Tumor Segmentation and Tracking in 3D Whole-Body Imaging](https://mlsanity.com/paper/2502.20985/) (2025)
- [VIBESegmentator: Full Body MRI Segmentation for the NAKO and UK Biobank](https://mlsanity.com/paper/2406.00125/) (2024)
- [Universal Segmentation of 33 Anatomies](https://mlsanity.com/paper/2203.02098/) (2022)
- [Learning with Explicit Shape Priors for Medical Image Segmentation](https://mlsanity.com/paper/2303.17967/) (2023)
- [Counterfactual Explanations for Medical Image Classification and Regression using Diffusion Autoencoder](https://mlsanity.com/paper/2408.01571/) (2024)

## Abstract (arXiv)

Vertebral labelling and segmentation are two fundamental tasks in an automated spine processing pipeline. Reliable and accurate processing of spine images is expected to benefit clinical decision-support systems for diagnosis, surgery planning, and population-based analysis on spine and bone health. However, designing automated algorithms for spine processing is challenging predominantly due to considerable variations in anatomy and acquisition protocols and due to a severe shortage of publicly available data. Addressing these limitations, the Large Scale Vertebrae Segmentation Challenge (VerSe) was organised in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) in 2019 and 2020, with a call for algorithms towards labelling and segmentation of vertebrae. Two datasets containing a total of 374 multi-detector CT scans from 355 patients were prepared and 4505 vertebrae have individually been annotated at voxel-level by a human-machine hybrid algorithm (https://osf.io/nqjyw/, https://osf.io/t98fz/). A total of 25 algorithms were benchmarked on these datasets. In this work, we present the the results of this evaluation and further investigate the performance-variation at vertebra-level, scan-level, and at different fields-of-view. We also evaluate the generalisability of the approaches to an implicit domain shift in data by evaluating the top performing algorithms of one challenge iteration on data from the other iteration. The principal takeaway from VerSe: the performance of an algorithm in labelling and segmenting a spine scan hinges on its ability to correctly identify vertebrae in cases of rare anatomical variations. The content and code concerning VerSe can be accessed at: https://github.com/anjany/verse.
