# Fully Unsupervised Probabilistic Noise2Void

arXiv: https://arxiv.org/abs/1911.12291 · HTML: https://mlsanity.com/paper/1911.12291/

## Key facts

- Cited by 14 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 27 Nov 2019.

## Built on by (most cited first, 14 of 14)

- [Dancing under the stars: video denoising in starlight](https://mlsanity.com/paper/2204.04210/) (2022)
- [DeFlow: Learning Complex Image Degradations from Unpaired Data with Conditional Flows](https://mlsanity.com/paper/2101.05796/) (2021)
- [Interpretable Unsupervised Diversity Denoising and Artefact Removal](https://mlsanity.com/paper/2104.01374/) (2021)
- [Unsupervised Deep Learning Methods for Biological Image Reconstruction and Enhancement](https://mlsanity.com/paper/2105.08040/) (2021)
- [Normalization-Equivariant Neural Networks with Application to Image Denoising](https://mlsanity.com/paper/2306.05037/) (2023)
- [N2V2 -- Fixing Noise2Void Checkerboard Artifacts with Modified Sampling Strategies and a Tweaked Network Architecture](https://mlsanity.com/paper/2211.08512/) (2022)
- [denoiSplit: a method for joint microscopy image splitting and unsupervised denoising](https://mlsanity.com/paper/2403.11854/) (2024)
- [Joint self-supervised blind denoising and noise estimation](https://mlsanity.com/paper/2102.08023/) (2021)
- [Contrastive Learning for Low-light Raw Denoising](https://mlsanity.com/paper/2305.03352/) (2023)
- [Image quality measurements and denoising using Fourier Ring Correlations](https://mlsanity.com/paper/2201.03992/) (2022)
- [Self-supervised regression learning using domain knowledge: Applications to improving self-supervised denoising in imaging](https://mlsanity.com/paper/2205.04821/) (2022)
- [Unsupervised Denoising for Signal-Dependent and Row-Correlated Imaging Noise](https://mlsanity.com/paper/2310.07887/) (2023)
- [On normalization-equivariance properties of supervised and unsupervised denoising methods: a survey](https://mlsanity.com/paper/2402.15352/) (2024)
- [Direct Unsupervised Denoising](https://mlsanity.com/paper/2310.18116/) (2023)

## Abstract (arXiv)

Image denoising is the first step in many biomedical image analysis pipelines and Deep Learning (DL) based methods are currently best performing. A new category of DL methods such as Noise2Void or Noise2Self can be used fully unsupervised, requiring nothing but the noisy data. However, this comes at the price of reduced reconstruction quality. The recently proposed Probabilistic Noise2Void (PN2V) improves results, but requires an additional noise model for which calibration data needs to be acquired. Here, we present improvements to PN2V that (i) replace histogram based noise models by parametric noise models, and (ii) show how suitable noise models can be created even in the absence of calibration data. This is a major step since it actually renders PN2V fully unsupervised. We demonstrate that all proposed improvements are not only academic but indeed relevant.