# BEHRT: Transformer for Electronic Health Records

arXiv: https://arxiv.org/abs/1907.09538 · HTML: https://mlsanity.com/paper/1907.09538/

## Key facts

- Cited by 263 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 22 Jul 2019.

## Built on by (most cited first, 30 of 263)

- [Multimodal Learning with Transformers: A Survey](https://mlsanity.com/paper/2206.06488/) (2022)
- [A Survey of Large Language Models for Healthcare: from Data, Technology, and Applications to Accountability and Ethics](https://mlsanity.com/paper/2310.05694/) (2023)
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- [AMMUS : A Survey of Transformer-based Pretrained Models in Natural Language Processing](https://mlsanity.com/paper/2108.05542/) (2021)
- [EHRSHOT: An EHR Benchmark for Few-Shot Evaluation of Foundation Models](https://mlsanity.com/paper/2307.02028/) (2023)
- [A Comprehensive Survey of Scientific Large Language Models and Their Applications in Scientific Discovery](https://mlsanity.com/paper/2406.10833/) (2024)
- [Pre-trained Language Models in Biomedical Domain: A Systematic Survey](https://mlsanity.com/paper/2110.05006/) (2021)
- [MOTOR: A Time-To-Event Foundation Model For Structured Medical Records](https://mlsanity.com/paper/2301.03150/) (2023)
- [Foundation Model for Advancing Healthcare: Challenges, Opportunities, and Future Directions](https://mlsanity.com/paper/2404.03264/) (2024)
- [CEHR-BERT: Incorporating temporal information from structured EHR data to improve prediction tasks](https://mlsanity.com/paper/2111.08585/) (2021)
- [Time Series Prediction using Deep Learning Methods in Healthcare](https://mlsanity.com/paper/2108.13461/) (2021)
- [Recovering Private Text in Federated Learning of Language Models](https://mlsanity.com/paper/2205.08514/) (2022)
- [Large AI Models in Health Informatics: Applications, Challenges, and the Future](https://mlsanity.com/paper/2303.11568/) (2023)
- [Hi-BEHRT: Hierarchical Transformer-based model for accurate prediction of clinical events using multimodal longitudinal electronic health records](https://mlsanity.com/paper/2106.11360/) (2021)
- [A Multimodal Transformer: Fusing Clinical Notes with Structured EHR Data for Interpretable In-Hospital Mortality Prediction](https://mlsanity.com/paper/2208.10240/) (2022)
- [Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Events](https://mlsanity.com/paper/2306.11547/) (2023)
- [A Transformer-based representation-learning model with unified processing of multimodal input for clinical diagnostics](https://mlsanity.com/paper/2306.00864/) (2023)
- [An Extensive Data Processing Pipeline for MIMIC-IV](https://mlsanity.com/paper/2204.13841/) (2022)
- [Context Clues: Evaluating Long Context Models for Clinical Prediction Tasks on EHRs](https://mlsanity.com/paper/2412.16178/) (2024)
- [GenHPF: General Healthcare Predictive Framework with Multi-task Multi-source Learning](https://mlsanity.com/paper/2207.09858/) (2022)
- [Neural Natural Language Processing for Unstructured Data in Electronic Health Records: a Review](https://mlsanity.com/paper/2107.02975/) (2021)
- [Deep learning for temporal data representation in electronic health records: A systematic review of challenges and methodologies](https://mlsanity.com/paper/2107.09951/) (2021)
- [CPLLM: Clinical Prediction with Large Language Models](https://mlsanity.com/paper/2309.11295/) (2023)
- [AMMU : A Survey of Transformer-based Biomedical Pretrained Language Models](https://mlsanity.com/paper/2105.00827/) (2021)
- [EHRMamba: Towards Generalizable and Scalable Foundation Models for Electronic Health Records](https://mlsanity.com/paper/2405.14567/) (2024)
- [A Multi-Center Study on the Adaptability of a Shared Foundation Model for Electronic Health Records](https://mlsanity.com/paper/2311.11483/) (2023)
- [MUFASA: Multimodal Fusion Architecture Search for Electronic Health Records](https://mlsanity.com/paper/2102.02340/) (2021)
- [Using Sequences of Life-events to Predict Human Lives](https://mlsanity.com/paper/2306.03009/) (2023)
- [INSPECT: A Multimodal Dataset for Pulmonary Embolism Diagnosis and Prognosis](https://mlsanity.com/paper/2311.10798/) (2023)
- [Data-Centric Foundation Models in Computational Healthcare: A Survey](https://mlsanity.com/paper/2401.02458/) (2024)

## Abstract (arXiv)

Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases, however, can provide patients and carers with the chance of early intervention, better disease management, and efficient allocation of healthcare resources. The latest developments in machine learning (more specifically, deep learning) provides a great opportunity to address this unmet need. In this study, we introduce BEHRT: A deep neural sequence transduction model for EHR (electronic health records), capable of multitask prediction and disease trajectory mapping. When trained and evaluated on the data from nearly 1.6 million individuals, BEHRT shows a striking absolute improvement of 8.0-10.8%, in terms of Average Precision Score, compared to the existing state-of-the-art deep EHR models (in terms of average precision, when predicting for the onset of 301 conditions). In addition to its superior prediction power, BEHRT provides a personalised view of disease trajectories through its attention mechanism; its flexible architecture enables it to incorporate multiple heterogeneous concepts (e.g., diagnosis, medication, measurements, and more) to improve the accuracy of its predictions; and its (pre-)training results in disease and patient representations that can help us get a step closer to interpretable predictions.
