# Prostate Cancer Detection using Deep Convolutional Neural Networks

arXiv: https://arxiv.org/abs/1905.13145 · HTML: https://mlsanity.com/paper/1905.13145/

## Key facts

- Cited by 15 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 30 May 2019.

## Built on by (most cited first, 15 of 15)

- [End-to-end Prostate Cancer Detection in bpMRI via 3D CNNs: Effects of Attention Mechanisms, Clinical Priori and Decoupled False Positive Reduction](https://mlsanity.com/paper/2101.03244/) (2021)
- [Deep Learning for fully automatic detection, segmentation, and Gleason Grade estimation of prostate cancer in multiparametric Magnetic Resonance Images](https://mlsanity.com/paper/2103.12650/) (2021)
- [MEDUSA: Multi-scale Encoder-Decoder Self-Attention Deep Neural Network Architecture for Medical Image Analysis](https://mlsanity.com/paper/2110.06063/) (2021)
- [Weakly supervised localisation of prostate cancer using reinforcement learning for bi-parametric MR images](https://mlsanity.com/paper/2402.13778/) (2024)
- [On the Feasibility of Machine Learning Augmented Magnetic Resonance for Point-of-Care Identification of Disease](https://mlsanity.com/paper/2301.11962/) (2023)
- [Tumor likelihood estimation on MRI prostate data by utilizing k-Space information](https://mlsanity.com/paper/2407.06165/) (2024)
- [Enhancing Clinically Significant Prostate Cancer Prediction in T2-weighted Images through Transfer Learning from Breast Cancer](https://mlsanity.com/paper/2405.07869/) (2024)
- [Influence of High-Performance Image-to-Image Translation Networks on Clinical Visual Assessment and Outcome Prediction: Utilizing Ultrasound to MRI Translation in Prostate Cancer](https://mlsanity.com/paper/2501.18109/) (2025)
- [Deep Learning Based Analysis of Prostate Cancer from MP-MRI](https://mlsanity.com/paper/2106.01835/) (2021)
- [Self-transfer learning via patches: A prostate cancer triage approach based on bi-parametric MRI](https://mlsanity.com/paper/2107.10806/) (2021)
- [Neural Networks for Infectious Diseases Detection: Prospects and Challenges](https://mlsanity.com/paper/2112.03571/) (2021)
- [Implementation of Convolutional Neural Network Architecture on 3D Multiparametric Magnetic Resonance Imaging for Prostate Cancer Diagnosis](https://mlsanity.com/paper/2112.14644/) (2021)
- [Domain Transfer Through Image-to-Image Translation for Uncertainty-Aware Prostate Cancer Classification](https://mlsanity.com/paper/2307.00479/) (2023)
- [Cancer-Net PCa-Gen: Synthesis of Realistic Prostate Diffusion Weighted Imaging Data via Anatomic-Conditional Controlled Latent Diffusion](https://mlsanity.com/paper/2311.18612/) (2023)
- [Diffusion MRI preprocessing affects ADC estimation and automatic PI-RADS v2.1 classification in bi-parametric prostate MRI](https://mlsanity.com/paper/2607.11385/) (2026)

## Abstract (arXiv)

Prostate cancer is one of the most common forms of cancer and the third leading cause of cancer death in North America. As an integrated part of computer-aided detection (CAD) tools, diffusion-weighted magnetic resonance imaging (DWI) has been intensively studied for accurate detection of prostate cancer. With deep convolutional neural networks (CNNs) significant success in computer vision tasks such as object detection and segmentation, different CNNs architectures are increasingly investigated in medical imaging research community as promising solutions for designing more accurate CAD tools for cancer detection. In this work, we developed and implemented an automated CNNs-based pipeline for detection of clinically significant prostate cancer (PCa) for a given axial DWI image and for each patient. DWI images of 427 patients were used as the dataset, which contained 175 patients with PCa and 252 healthy patients. To measure the performance of the proposed pipeline, a test set of 108 (out of 427) patients were set aside and not used in the training phase. The proposed pipeline achieved area under the receiver operating characteristic curve (AUC) of 0.87 (95% Confidence Interval (CI): 0.84-0.90) and 0.84 (95% CI: 0.76-0.91) at slice level and patient level, respectively.
