# Towards causally interpretable meta-analysis: transporting inferences from multiple studies to a target population

arXiv: https://arxiv.org/abs/1903.11455 · HTML: https://mlsanity.com/paper/1903.11455/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 27 Mar 2019.

## Built on by (most cited first, 1 of 1)

- [The s-value: evaluating stability with respect to distributional shifts](https://mlsanity.com/paper/2105.03067/) (2021)

## Abstract (arXiv)

We take steps towards causally interpretable meta-analysis by describing methods for transporting causal inferences from a collection of randomized trials to a new target population, one-trial-at-a-time and pooling all trials. We discuss identifiability conditions for average treatment effects in the target population and provide identification results. We show that assuming inferences are transportable from all trials in the collection to the same target population has implications for the law underlying the observed data. We propose average treatment effect estimators that rely on different working models and provide code for their implementation in statistical software. We discuss how to use the data to examine whether transported inferences are homogeneous across the collection of trials, sketch approaches for sensitivity analysis to violations of the identifiability conditions, and describe extensions to address non-adherence in the trials. Last, we illustrate the proposed methods using data from the HALT-C multi-center trial.
