# High-fidelity, high-isotropic resolution diffusion imaging through gSlider acquisition with B1+ & T1 corrections and integrated DeltaB0/Rx shim array

arXiv: https://arxiv.org/abs/1811.05473 · HTML: https://mlsanity.com/paper/1811.05473/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 13 Nov 2018.

## Built on by (most cited first, 4 of 4)

- [SDnDTI: Self-supervised deep learning-based denoising for diffusion tensor MRI](https://mlsanity.com/paper/2111.07220/) (2021)
- [SRDTI: Deep learning-based super-resolution for diffusion tensor MRI](https://mlsanity.com/paper/2102.09069/) (2021)
- [Artificial Intelligence for Neuro MRI Acquisition: A Review](https://mlsanity.com/paper/2406.05982/) (2024)
- [A physics-informed foundation model for quantitative diffusion MRI](https://mlsanity.com/paper/2606.00156/) (2026)

## Abstract (arXiv)

Purpose: B1+ and T1 corrections and dynamic multi-coil shimming approaches were proposed to improve the fidelity of high isotropic resolution Generalized slice dithered enhanced resolution (gSlider) diffusion imaging. Methods: An extended reconstruction incorporating B1+ inhomogeneity and T1 recovery information was developed to mitigate slab-boundary artifacts in short-TR gSlider acquisitions. Slab-by-slab dynamic B0 shimming using a multi-coil integrated DeltaB0/Rx shim-array, and high in-plane acceleration (Rinplane=4) achieved with virtual-coil GRAPPA were also incorporated into a 1 mm isotropic resolution gSlider acquisition/reconstruction framework to achieve an 8-11 fold reduction in geometric distortion compared to single-shot EPI. Results: The slab-boundary artifacts were alleviated by the proposed B1+ and T1 corrections compared to the standard gSlider reconstruction pipeline for short-TR acquisitions. Dynamic shimming provided >50% reduction in geometric distortion compared to conventional global 2nd order shimming. 1 mm isotropic resolution diffusion data show that the typically problematic temporal and frontal lobes of the brain can be imaged with high geometric fidelity using dynamic shimming. Conclusions: The proposed B1+ and T1 corrections and local-field control substantially improved the fidelity of high isotropic resolution diffusion imaging, with reduced slab-boundary artifacts and geometric distortion compared to conventional gSlider acquisition and reconstruction. This enabled high-fidelity whole-brain 1 mm isotropic diffusion imaging with 64 diffusion-directions in 20 minutes using a 3T clinical scanner.