# Analyzing biological and artificial neural networks: challenges with opportunities for synergy?

arXiv: https://arxiv.org/abs/1810.13373 · HTML: https://mlsanity.com/paper/1810.13373/

## Key facts

- Cited by 20 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 31 Oct 2018.

## Built on by (most cited first, 20 of 20)

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- [Stretching Beyond the Obvious: A Gradient-Free Framework to Unveil the Hidden Landscape of Visual Invariance](https://mlsanity.com/paper/2506.17040/) (2025)
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## Abstract (arXiv)

Deep neural networks (DNNs) transform stimuli across multiple processing stages to produce representations that can be used to solve complex tasks, such as object recognition in images. However, a full understanding of how they achieve this remains elusive. The complexity of biological neural networks substantially exceeds the complexity of DNNs, making it even more challenging to understand the representations that they learn. Thus, both machine learning and computational neuroscience are faced with a shared challenge: how can we analyze their representations in order to understand how they solve complex tasks? We review how data-analysis concepts and techniques developed by computational neuroscientists can be useful for analyzing representations in DNNs, and in turn, how recently developed techniques for analysis of DNNs can be useful for understanding representations in biological neural networks. We explore opportunities for synergy between the two fields, such as the use of DNNs as in-silico model systems for neuroscience, and how this synergy can lead to new hypotheses about the operating principles of biological neural networks.
