# Deep multiscale convolutional feature learning for weakly supervised localization of chest pathologies in X-ray images

arXiv: https://arxiv.org/abs/1808.08280 · HTML: https://mlsanity.com/paper/1808.08280/

## Key facts

- Cited by 12 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 22 Aug 2018.

## Built on by (most cited first, 12 of 12)

- [Explainable artificial intelligence (XAI) in deep learning-based medical image analysis](https://mlsanity.com/paper/2107.10912/) (2021)
- [Interpretability-Driven Sample Selection Using Self Supervised Learning For Disease Classification And Segmentation](https://mlsanity.com/paper/2104.06087/) (2021)
- [CT Image Synthesis Using Weakly Supervised Segmentation and Geometric Inter-Label Relations For COVID Image Analysis](https://mlsanity.com/paper/2106.10230/) (2021)
- [Weakly-supervised High-resolution Segmentation of Mammography Images for Breast Cancer Diagnosis](https://mlsanity.com/paper/2106.07049/) (2021)
- [Learning of Inter-Label Geometric Relationships Using Self-Supervised Learning: Application To Gleason Grade Segmentation](https://mlsanity.com/paper/2110.00404/) (2021)
- [Unsupervised Domain Adaptation Using Feature Disentanglement And GCNs For Medical Image Classification](https://mlsanity.com/paper/2206.13123/) (2022)
- [Multimodal Generalized Zero Shot Learning for Gleason Grading using Self-Supervised Learning](https://mlsanity.com/paper/2111.07646/) (2021)
- [GREN: Graph-Regularized Embedding Network for Weakly-Supervised Disease Localization in X-ray Images](https://mlsanity.com/paper/2107.06442/) (2021)
- [Interpretable Saliency Maps And Self-Supervised Learning For Generalized Zero Shot Medical Image Classification](https://mlsanity.com/paper/2204.01728/) (2022)
- [Improved Super Resolution of MR Images Using CNNs and Vision Transformers](https://mlsanity.com/paper/2207.11748/) (2022)
- [CLARiTy: A Vision Transformer for Multi-Label Classification and Weakly-Supervised Localization of Chest X-ray Pathologies](https://mlsanity.com/paper/2512.16700/) (2025)
- [Cyclic Generative Adversarial Networks With Congruent Image-Report Generation For Explainable Medical Image Analysis](https://mlsanity.com/paper/2211.08424/) (2022)

## Abstract (arXiv)

Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale feature learning. Our method leverages intermediate feature maps from CNN layers at different stages of a deep network during the training of a classification model using image level annotations of pathologies. During the training phase, a set of layer relevance weights are learned for each pathology class and the CNN is optimized to perform pathology classification by convex combination of feature maps from both shallow and deep layers using the learned weights. During the test phase, to localize the predicted pathology, the multiscale attention map is obtained by convex combination of class activation maps from each stage using the layer relevance weights learned during the training phase. We have validated our method using 112000 X-ray images and compared with the state-of-the-art localization methods. We experimentally demonstrate that the proposed weakly supervised method can improve the localization performance of small pathologies such as nodule and mass while giving comparable performance for bigger pathologies e.g., Cardiomegaly
