# Rotation Equivariant CNNs for Digital Pathology

arXiv: https://arxiv.org/abs/1806.03962 · HTML: https://mlsanity.com/paper/1806.03962/

## Key facts

- Cited by 422 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 8 Jun 2018.

## Built on by (most cited first, 30 of 422)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Visual Prompt Tuning](https://mlsanity.com/paper/2203.12119/) (2022)
- [Vision-Language Models for Vision Tasks: A Survey](https://mlsanity.com/paper/2304.00685/) (2023)
- [EVA-CLIP: Improved Training Techniques for CLIP at Scale](https://mlsanity.com/paper/2303.15389/) (2023)
- [Scaling Vision with Sparse Mixture of Experts](https://mlsanity.com/paper/2106.05974/) (2021)
- [FLAVA: A Foundational Language And Vision Alignment Model](https://mlsanity.com/paper/2112.04482/) (2021)
- [DataComp: In search of the next generation of multimodal datasets](https://mlsanity.com/paper/2304.14108/) (2023)
- [BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs](https://mlsanity.com/paper/2303.00915/) (2023)
- [SLIP: Self-supervision meets Language-Image Pre-training](https://mlsanity.com/paper/2112.12750/) (2021)
- [EVA-02: A Visual Representation for Neon Genesis](https://mlsanity.com/paper/2303.11331/) (2023)
- [Scaling & Shifting Your Features: A New Baseline for Efficient Model Tuning](https://mlsanity.com/paper/2210.08823/) (2022)
- [Quilt-1M: One Million Image-Text Pairs for Histopathology](https://mlsanity.com/paper/2306.11207/) (2023)
- [Combined Scaling for Zero-shot Transfer Learning](https://mlsanity.com/paper/2111.10050/) (2021)
- [Virchow2: Scaling Self-Supervised Mixed Magnification Models in Pathology](https://mlsanity.com/paper/2408.00738/) (2024)
- [Finetune like you pretrain: Improved finetuning of zero-shot vision models](https://mlsanity.com/paper/2212.00638/) (2022)
- [Benchmarking Self-Supervised Learning on Diverse Pathology Datasets](https://mlsanity.com/paper/2212.04690/) (2022)
- [Task Singular Vectors: Reducing Task Interference in Model Merging](https://mlsanity.com/paper/2412.00081/) (2024)
- [ELEVATER: A Benchmark and Toolkit for Evaluating Language-Augmented Visual Models](https://mlsanity.com/paper/2204.08790/) (2022)
- [The Benchmark Lottery](https://mlsanity.com/paper/2107.07002/) (2021)
- [Neural Prompt Search](https://mlsanity.com/paper/2206.04673/) (2022)
- [FacT: Factor-Tuning for Lightweight Adaptation on Vision Transformer](https://mlsanity.com/paper/2212.03145/) (2022)
- [Localizing Task Information for Improved Model Merging and Compression](https://mlsanity.com/paper/2405.07813/) (2024)
- [Convolutional Bypasses Are Better Vision Transformer Adapters](https://mlsanity.com/paper/2207.07039/) (2022)
- [Robust CLIP: Unsupervised Adversarial Fine-Tuning of Vision Embeddings for Robust Large Vision-Language Models](https://mlsanity.com/paper/2402.12336/) (2024)
- [Understanding Zero-Shot Adversarial Robustness for Large-Scale Models](https://mlsanity.com/paper/2212.07016/) (2022)
- [Scalable Pre-training of Large Autoregressive Image Models](https://mlsanity.com/paper/2401.08541/) (2024)
- [Chinese CLIP: Contrastive Vision-Language Pretraining in Chinese](https://mlsanity.com/paper/2211.01335/) (2022)
- [Multimodal Autoregressive Pre-training of Large Vision Encoders](https://mlsanity.com/paper/2411.14402/) (2024)
- [HEST-1k: A Dataset for Spatial Transcriptomics and Histology Image Analysis](https://mlsanity.com/paper/2406.16192/) (2024)
- [AUC Maximization in the Era of Big Data and AI: A Survey](https://mlsanity.com/paper/2203.15046/) (2022)

## Abstract (arXiv)

We propose a new model for digital pathology segmentation, based on the observation that histopathology images are inherently symmetric under rotation and reflection. Utilizing recent findings on rotation equivariant CNNs, the proposed model leverages these symmetries in a principled manner. We present a visual analysis showing improved stability on predictions, and demonstrate that exploiting rotation equivariance significantly improves tumor detection performance on a challenging lymph node metastases dataset. We further present a novel derived dataset to enable principled comparison of machine learning models, in combination with an initial benchmark. Through this dataset, the task of histopathology diagnosis becomes accessible as a challenging benchmark for fundamental machine learning research.
