# A Scalable Discrete-Time Survival Model for Neural Networks

arXiv: https://arxiv.org/abs/1805.00917 · HTML: https://mlsanity.com/paper/1805.00917/

## Key facts

- Cited by 72 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 2 May 2018.

## Built on by (most cited first, 30 of 72)

- [Deep Learning for Survival Analysis: A Review](https://mlsanity.com/paper/2305.14961/) (2023)
- [SurvITE: Learning Heterogeneous Treatment Effects from Time-to-Event Data](https://mlsanity.com/paper/2110.14001/) (2021)
- [Net benefit, calibration, threshold selection, and training objectives for algorithmic fairness in healthcare](https://mlsanity.com/paper/2202.01906/) (2022)
- [DeepPAMM: Deep Piecewise Exponential Additive Mixed Models for Complex Hazard Structures in Survival Analysis](https://mlsanity.com/paper/2202.07423/) (2022)
- [DeepMTS: Deep Multi-task Learning for Survival Prediction in Patients with Advanced Nasopharyngeal Carcinoma using Pretreatment PET/CT](https://mlsanity.com/paper/2109.07711/) (2021)
- [DRIM: Learning Disentangled Representations from Incomplete Multimodal Healthcare Data](https://mlsanity.com/paper/2409.17055/) (2024)
- [Survival Kernets: Scalable and Interpretable Deep Kernel Survival Analysis with an Accuracy Guarantee](https://mlsanity.com/paper/2206.10477/) (2022)
- [Survival Mixture Density Networks](https://mlsanity.com/paper/2208.10759/) (2022)
- [Merging-Diverging Hybrid Transformer Networks for Survival Prediction in Head and Neck Cancer](https://mlsanity.com/paper/2307.03427/) (2023)
- [DySurv: dynamic deep learning model for survival analysis with conditional variational inference](https://mlsanity.com/paper/2310.18681/) (2023)
- [Tabular Foundation Models Can Do Survival Analysis](https://mlsanity.com/paper/2601.22259/) (2026)
- [T-SCI: A Two-Stage Conformal Inference Algorithm with Guaranteed Coverage for Cox-MLP](https://mlsanity.com/paper/2103.04556/) (2021)
- [Inverse-Weighted Survival Games](https://mlsanity.com/paper/2111.08175/) (2021)
- [Federated Survival Forests](https://mlsanity.com/paper/2302.02807/) (2023)
- [BDNNSurv: Bayesian deep neural networks for survival analysis using pseudo values](https://mlsanity.com/paper/2101.03170/) (2021)
- [Avoiding C-hacking when evaluating survival distribution predictions with discrimination measures](https://mlsanity.com/paper/2112.04828/) (2021)
- [BITES: Balanced Individual Treatment Effect for Survival data](https://mlsanity.com/paper/2201.03448/) (2022)
- [Conditional Distribution Function Estimation Using Neural Networks for Censored and Uncensored Data](https://mlsanity.com/paper/2207.02384/) (2022)
- [Scaling Survival Analysis in Healthcare with Federated Survival Forests: A Comparative Study on Heart Failure and Breast Cancer Genomics](https://mlsanity.com/paper/2308.02382/) (2023)
- [Interpretable Prediction of Lung Squamous Cell Carcinoma Recurrence With Self-supervised Learning](https://mlsanity.com/paper/2203.12204/) (2022)
- [Predicting Time-to-conversion for Dementia of Alzheimer's Type using Multi-modal Deep Survival Analysis](https://mlsanity.com/paper/2205.01188/) (2022)
- [Contrastive Learning of Temporal Distinctiveness for Survival Analysis in Electronic Health Records](https://mlsanity.com/paper/2308.13104/) (2023)
- [Dynamic Survival Analysis for Early Event Prediction](https://mlsanity.com/paper/2403.12818/) (2024)
- [NeuralSurv: Deep Survival Analysis with Bayesian Uncertainty Quantification](https://mlsanity.com/paper/2505.11054/) (2025)
- [A Federated Cox Model with Non-Proportional Hazards](https://mlsanity.com/paper/2207.05050/) (2022)
- [Toward a Well-Calibrated Discrimination via Survival Outcome-Aware Contrastive Learning](https://mlsanity.com/paper/2410.11340/) (2024)
- [AdaMSS: Adaptive Multi-Modality Segmentation-to-Survival Learning for Survival Outcome Prediction from PET/CT Images](https://mlsanity.com/paper/2305.09946/) (2023)
- [Multimodal Masked Autoencoder Pre-training for 3D MRI-Based Brain Tumor Analysis with Missing Modalities](https://mlsanity.com/paper/2505.00568/) (2025)
- [SVL: Goal-Conditioned Reinforcement Learning as Survival Learning](https://mlsanity.com/paper/2604.17551/) (2026)
- [Multimodal Deep Learning for Personalized Renal Cell Carcinoma Prognosis: Integrating CT Imaging and Clinical Data](https://mlsanity.com/paper/2307.03575/) (2023)

## Abstract (arXiv)

There is currently great interest in applying neural networks to prediction tasks in medicine. It is important for predictive models to be able to use survival data, where each patient has a known follow-up time and event/censoring indicator. This avoids information loss when training the model and enables generation of predicted survival curves. In this paper, we describe a discrete-time survival model that is designed to be used with neural networks, which we refer to as Nnet-survival. The model is trained with the maximum likelihood method using minibatch stochastic gradient descent (SGD). The use of SGD enables rapid convergence and application to large datasets that do not fit in memory. The model is flexible, so that the baseline hazard rate and the effect of the input data on hazard probability can vary with follow-up time. It has been implemented in the Keras deep learning framework, and source code for the model and several examples is available online. We demonstrate the performance of the model on both simulated and real data and compare it to existing models Cox-nnet and Deepsurv.
