# Parameter Estimation, Sensitivity Analysis and Optimal Control of a Periodic Epidemic Model with Application to HRSV in Florida

arXiv: https://arxiv.org/abs/1801.09634 · HTML: https://mlsanity.com/paper/1801.09634/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 29 Jan 2018.

## Built on by (most cited first, 1 of 1)

- [Resource Planning for Hospitals Under Special Consideration of the COVID-19 Pandemic: Optimization and Sensitivity Analysis](https://mlsanity.com/paper/2105.07420/) (2021)

## Abstract (arXiv)

A state wide Human Respiratory Syncytial Virus (HRSV) surveillance system was implemented in Florida in 1999 to support clinical decision-making for prophylaxis of premature infants. The research presented in this paper addresses the problem of fitting real data collected by the Florida HRSV surveillance system by using a periodic SEIRS mathematical model. A sensitivity and cost-effectiveness analysis of the model is done and an optimal control problem is formulated and solved with treatment as the control variable.