# Predicting Clinical Events by Combining Static and Dynamic Information Using Recurrent Neural Networks

arXiv: https://arxiv.org/abs/1602.02685 · HTML: https://mlsanity.com/paper/1602.02685/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 8 Feb 2016.

## Built on by (most cited first, 9 of 9)

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- [Modeling Long-term Dependencies and Short-term Correlations in Patient Journey Data with Temporal Attention Networks for Health Prediction](https://mlsanity.com/paper/2207.06414/) (2022)
- [Adaptive Nonlinear Vector Autoregression: Robust Forecasting for Noisy Chaotic Time Series](https://mlsanity.com/paper/2507.08738/) (2025)
- [A machine learning framework for interpretable predictions in patient pathways: The case of predicting ICU admission for patients with symptoms of sepsis](https://mlsanity.com/paper/2405.13187/) (2024)
- [An attention model to analyse the risk of agitation and urinary tract infections in people with dementia](https://mlsanity.com/paper/2101.07007/) (2021)
- [Developing hybrid mechanistic and data-driven personalized prediction models for platelet dynamics](https://mlsanity.com/paper/2505.21204/) (2025)

## Abstract (arXiv)

In clinical data sets we often find static information (e.g. patient gender, blood type, etc.) combined with sequences of data that are recorded during multiple hospital visits (e.g. medications prescribed, tests performed, etc.). Recurrent Neural Networks (RNNs) have proven to be very successful for modelling sequences of data in many areas of Machine Learning. In this work we present an approach based on RNNs, specifically designed for the clinical domain, that combines static and dynamic information in order to predict future events. We work with a database collected in the Charit'e Hospital in Berlin that contains complete information concerning patients that underwent a kidney transplantation. After the transplantation three main endpoints can occur: rejection of the kidney, loss of the kidney and death of the patient. Our goal is to predict, based on information recorded in the Electronic Health Record of each patient, whether any of those endpoints will occur within the next six or twelve months after each visit to the clinic. We compared different types of RNNs that we developed for this work, with a model based on a Feedforward Neural Network and a Logistic Regression model. We found that the RNN that we developed based on Gated Recurrent Units provides the best performance for this task. We also used the same models for a second task, i.e., next event prediction, and found that here the model based on a Feedforward Neural Network outperformed the other models. Our hypothesis is that long-term dependencies are not as relevant in this task.