# Temporal Convolutional Neural Networks for Diagnosis from Lab Tests

arXiv: https://arxiv.org/abs/1511.07938 · HTML: https://mlsanity.com/paper/1511.07938/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 25 Nov 2015.

## Built on by (most cited first, 6 of 6)

- [Deep Imputation of Missing Values in Time Series Health Data: A Review with Benchmarking](https://mlsanity.com/paper/2302.10902/) (2023)
- [Conditional Generation of Medical Time Series for Extrapolation to Underrepresented Populations](https://mlsanity.com/paper/2201.08186/) (2022)
- [Supervised multi-specialist topic model with applications on large-scale electronic health record data](https://mlsanity.com/paper/2105.01238/) (2021)
- [Conformal Agent Error Attribution](https://mlsanity.com/paper/2605.06788/) (2026)
- [AdaFSNet: Time Series Classification Based on Convolutional Network with a Adaptive and Effective Kernel Size Configuration](https://mlsanity.com/paper/2404.18246/) (2024)
- [Personalized Understanding of Blood Glucose Dynamics via Mobile Sensor Data](https://mlsanity.com/paper/2302.01400/) (2023)

## Abstract (arXiv)

Early diagnosis of treatable diseases is essential for improving healthcare, and many diseases' onsets are predictable from annual lab tests and their temporal trends. We introduce a multi-resolution convolutional neural network for early detection of multiple diseases from irregularly measured sparse lab values. Our novel architecture takes as input both an imputed version of the data and a binary observation matrix. For imputing the temporal sparse observations, we develop a flexible, fast to train method for differentiable multivariate kernel regression. Our experiments on data from 298K individuals over 8 years, 18 common lab measurements, and 171 diseases show that the temporal signatures learned via convolution are significantly more predictive than baselines commonly used for early disease diagnosis.
