# A space-time conditional intensity model for invasive meningococcal disease occurrence

arXiv: https://arxiv.org/abs/1508.05740 · HTML: https://mlsanity.com/paper/1508.05740/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- First posted on arXiv 24 Aug 2015.

## Built on by (most cited first, 9 of 9)

- [Neural Flows: Efficient Alternative to Neural ODEs](https://mlsanity.com/paper/2110.13040/) (2021)
- [Spatio-temporal Diffusion Point Processes](https://mlsanity.com/paper/2305.12403/) (2023)
- [Integration-free Training for Spatio-temporal Multimodal Covariate Deep Kernel Point Processes](https://mlsanity.com/paper/2310.05485/) (2023)
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- [Beyond Hawkes: Neural Multi-event Forecasting on Spatio-temporal Point Processes](https://mlsanity.com/paper/2211.02922/) (2022)
- [Deep spatio-temporal point processes: Advances and new directions](https://mlsanity.com/paper/2504.06364/) (2025)
- [Statistical learning and cross-validation for point processes](https://mlsanity.com/paper/2103.01356/) (2021)
- [Long-range Modeling and Processing of Multimodal Event Sequences](https://mlsanity.com/paper/2602.01125/) (2026)
- [On Observation Time for Recovering Latent Hawkes Networks](https://mlsanity.com/paper/2605.08400/) (2026)

## Abstract (arXiv)

A novel point process model continuous in space-time is proposed for quantifying the transmission dynamics of the two most common meningococcal antigenic sequence types observed in Germany 2002-2008. Modelling is based on the conditional intensity function (CIF) which is described by a superposition of additive and multiplicative components. As an epidemiological interesting finding, spread behaviour was shown to depend on type in addition to age: basic reproduction numbers were 0.25 (95% CI 0.19-0.34) and 0.11 (95% CI 0.07-0.17) for types B:P1.7-2,4:F1-5 and C:P1.5,2:F3-3, respectively. Altogether, the proposed methodology represents a comprehensive and universal regression framework for the modelling, simulation and inference of self-exciting spatio-temporal point processes based on the CIF. Usability of the modelling in biometric practice is promoted by an implementation in the R package surveillance.
